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Model for an essential signal transduction network regulating cell cycle events in Caulobacter. The cell cycle-regulated activity of CtrA is modulated by a signal transduction network, including the DivJ-dependent phosphorelay pathway described previously (23) and directly or indirectly by the DivL kinase described in this paper. As demonstrated for transcription of class II flagellar genes in vitro (23), we assume that CtrA is activated by phosphorylation.
