Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of Inflammatory biomarkers secreted by monocytes isolated from individuals with and without severe PiZZ AAT-deficiency
| Measured Biomarker | PiMM | PiZZ | Significance | ||
| Mean | SD | Mean | SD | P | |
| MMP-9 (ng/ml) | 5 | 1.9 | 4.4 | 1 | 0.3 |
| MCP-1 (pg/ml) | 498 | 124 | 348 | 95 | 0.06 |
| ICAM-1(ng/ml) | 130 | 13 | 145 | 14 | 0.45 |
| TNF-α (pg/ml) | 12.8 | 9 | 5.7 | 2.5 | 0.029 |
| MIF (pg/ml) | 1315 | 192 | 1179 | 264 | 0.34 |
| IL-6 (pg/ml) | 18 | 1.9 | 18.4 | 3 | 0.414 |
| IL-1β (pg/ml) | 5.9 | 3 | 3 | 0.9 | 0.14 |
| IL-8 (pg/ml) | 2.2 | 0.4 | 2.5 | 0.47 | 0.843 |
