TABLE 5.
Protein names, domain names, and functions encoded by the loci identified in this study
Protein | Domain | Function |
---|---|---|
CHD1 | Chromodomain | Chromatin compaction, gene silencing (also found in HP1, PC) |
DNA binding | Binds (A + T) minor grooves | |
ATPase/helicase | Activates transcription via chromatin conformational changes | |
SSRP1 | HMG box | DNA/chromatin binding |
CHM | MYST | Acetyltransferase (transfers acetyl groups to histone tails) |
SMC4 | ATPase | Chromatin condensation (in combination with other condensing components) |
ATP binding | Chromatin condensation (in combination with other condensing components) |