Figure 5.—

Using comparative genomics and interval-specific haplotype analysis to narrow the chromosome 2 QTL. Comparing the C.I. of our cross with the interval on rat Chr 3 found in the (FHH × ACI) F₂ intercross and the human chromosome 20 interval narrowed the region to 51 Mb. Interval-specific haplotype analysis of this region, comparing SNPs between B6 and A, resulted in three regions that have different haplotypes between the strains and contain 343 genes according to the Ensembl database (release 42).