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. 2008 Jun 6;4(6):e1000083. doi: 10.1371/journal.ppat.1000083

Table 1. Genes differentially expressed in the presence of ciprofloxacin.

Gene ID and Functional Category P-Value Q-Value n-Fold change
Microarray qRT-PCR
Cell membrane
Cj0205 uppP, undecaprenyl-diphosphatase 0.0135 0.130143 1.59 6.1
Cj0735 putative periplasmic protein 0.0186 0.14811 1.70 NT*
Cj0824 uppS, undecaprenyl diphosphate synthase 0.0099 0.120356 1.52 2.1
Cj1351 pldA, phospholipase A 0.0046 0.094812 2.02 2
Cj0033 putative integral membrane protein 0.0033 0.086471 −1.52 NT
Cj0179 exbB1, biopolymer transport protein 0.0412 0.217646 −1.88 NT
Cj0486 putative sugar transporter 0.0043 0.091967 −1.57 NT
Cj0553 putative integral membrane protein 0.0106 0.121714 −1.59 NT
Cj0834c ankyrin repeat-containing possible periplasmic protein 0.0089 0.110719 −1.51 NT
Cj1013c putative cytochrome C biogenesis protein 0.0058 0.096095 −1.52 NT
Cj1662 putative integral membrane protein 0.0055 0.096095 −1.68 NT
Cj1663 putative ABC transport system ATP-binding protein 0.0002 0.067622 −1.75 NT
DNA replication, recombination and repair
Cj1085c mfd, transcription-repair coupling factor 0.0029 0.082832 1.57 2.2
Cj0718 dnaE, DNA polymerase III, alpha chain 4.07E-05 0.052459 −1.62 −1.98
Cellular process and energy metabolism
Cj0041 putative flagellar hook-length control protein 0.0357 0.204764 1.93 NT
Cj0065c folk, putative 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 0.0117 0.129371 1.54 NT
Cj1030c lepA, GTP-binding protein homolog 0.0057 0.210454 1.54 NT
Cj1280c putative ribosomal pseudouridine synthase 0.0252 0.170564 1.50 NT
Cj0009 gltd, glutamate synthase (NADPH) small subunit 0.0007 0.067622 −1.74 NT
Cj0123c putative tRNA-dihydrouridine synthase 0.0020 0.076881 −1.87 −2.1
Cj0227 argD, acetylornithine aminotransferase 0.0208 0.151677 −1.69 NT
Cj0283c cheW, chemotaxis protein 0.0125 0.130143 −1.52 NT
Cj0415 putative GMC oxidoreductase subunit 0.0191 0.148174 −1.53 NT
Cj0490- ald, putative aldehyde dehydrogenase C-terminus 0.0013 0.076653 −1.80 NT
Cj0537 oorb, OORB subunit of 2-oxoglutarate:acceptor oxidoreductase 0.0024 0.076881 −1.67 −2.23
Cj0734c hisJ, histidine-binding protein precursor 0.0404 0.214389 −1.59 NT
Cj0764c speA, biosynthetic arginine decarboxylase 0.0116 0.129371 −1.97 −1.96
Cj0767c kdtB,3-deoxy-D-manno-octulosonic-acid transferase 0.0370 0.207688 −1.58 NT
Cj1264c hydD, putative hydrogenase maturation protease 0.0009 0.067622 −2.13 −6.7
Cj1265c hydC, Ni/Fe-hydrogenase B-type cytochrome subunit 0.0016 0.076881 −2.12 NT
Cj1266c hydB, Ni/Fe-hydrogenase large subunit 0.0032 0.086244 −1.56 NT
Cj1364c fumC, fumarate hydratase 0.0255 0.171473 −1.52 NT
Cj1476c pyruvate-flavodoxin oxidoreductase 0.0133 0.130143 −1.55 NT
Cj1566c nuoN, NADH dehydrogenase I chain N 0.0039 0.088549 −2.03 −2.71
Cj1567c nuoM, NADH dehydrogenase I chain M 0.0055 0.096095 −1.60 NT
Cj1624c sdaA, L-serine dehydratase 0.0046 0.094812 −1.58 NT
Cj1682c gltA, citrate synthase 0.0167 0.142007 −1.54 NT
Cj1688c secY, preprotein translocase subunit 0.0021 0.076881 −1.63 −2.15
Cj1717c leuC, 3-isopropylmalate dehydratase large subunit 0.0018 0.076881 −1.61 NT
Unknown function
Cj0163c hypothetical protein 0.0204 0.151393 1.60 NT
Cj0814 hypothetical protein 0.0002 0.067622 1.99 NT
Cj0959c hypothetical protein 0.0233 0.160562 1.50 NT
Cj1025c hypothetical protein 0.0389 0.210454 1.54 NT
Cj0125c hypothetical protein Cj0125c 0.0031 0.084482 −1.53 NT
Cj0554 hypothetical protein 0.0083 0.107589 −1.71 NT

*: NT: Not tested.