Figure 5. Effect of TGF²1 on TNF± mRNA expression in astrocytes.
Astrocyte cultures were treated with either 3 ng/mL TGFβ1 alone (A) or 2 µg/mL LPS plus 3 ng/mL IFNγ (B) and total RNA was harvested at the times indicated. TNFα and β-actin mRNA levels were assessed via RT-PCR (see “Experimental Procedures”). CON = PCR reaction mix minus cDNA. Results are representative of two separate experiments on cultures from independent dissections.