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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Alzheimers Dement. 2008 Mar;4(2):134–144. doi: 10.1016/j.jalz.2008.01.001

Table 5.

Unadjusted and Adjusted Hazard Ratios for 2-Year Mortality, 1993 and 2002 Cohorts

1993
2002
Unadjusted Age- and Sex-Adjusted Fully-Adjusted Unadjusted Age- and Sex-Adjusted Fully-Adjusted
Cognitive Function
 Normal Ref. Ref. Ref Ref. Ref. Ref.
 Mild CI 2.24 (1.85 – 2.72) 1.90 (1.56 – 2.30) 1.57 (1.23 – 2.00) 2.16 (1.59 – 2.94) 1.82 (1.34 – 2.47) 1.03 (0.65 – 1.65)
 Mod / Sev CI 3.36 (2.74 – 4.13) 2.53 (2.04 – 3.14) 1.84 (1.41 – 2.40) 4.12* (3.22 – 5.26) 3.11 (2.34 – 4.12) 1.88 (1.33 – 2.65)
Education (years)
 < 12 Ref. Ref.
 12 0.86 (0.70 – 1.04) 0.82 (0.66 – 1.02)
 13 – 15 0.85 (0.68 – 1.06) 0.64 (0.51 – 0.81)
 ≥ 16 0.84 (0.59 – 1.21) 0.88 (0.66 – 1.19)
Cog Function X Education
 Mild CI X 12 1.44 (0.70 – 2.95) 3.65 (1.74 – 7.67)
 Mild CI X 13 – 15 0.63 (0.06 – 6.59) 2.87 (1.05 – 7.90)
 Mild CI X ≥ 16 2.25 (0.95 – 5.34) 0.40 (0.04 – 3.73)
 Mod / Sev CI X 12 1.85 (1.05 – 3.28) 1.71 (0.85 – 3.44)
 Mod / Sev CI X 13 – 15 2.69 (1.20 – 6.00) 2.93 (1.06 – 8.07)
 Mod / Sev CI X ≥ 16 1.14 (0.32 – 4.05) 2.44 (0.78 – 7.62)

Fully-adjusted model includes cognitive function, age, race, gender, net worth, education, potential caregiver network, chronic conditions, smoking status, and cognitive function X education level interaction terms.

CI is cognitive impairment.

95% Confidence intervals are in parentheses.

*

P=0.08 for comparison of unadjusted HR in 2002 vs. 1993 (4.12 vs. 3.36).

P=0.09 for comparison of age- and sex-adjusted HR in 2002 vs. 1993 (3.11 vs. 2.53).

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