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. Author manuscript; available in PMC: 2008 May 21.
Published in final edited form as: Exp Biol Med (Maywood). 2007 Nov;232(10):1338–1354. doi: 10.3181/0705-RM-148

Figure 4.

Figure 4

Pharmacokinetics of i.v. and orally administered PAP-1 in RM. (A) Total PAP-1 plasma concentration-time profile in RM after single i.v. injection of 3 mg/kg dose (left) and log plot of averaged data used to determine the volume of distribution (right). (B) Plasma concentration-time profile in RM that were orally administered 25 mg/kg of PAP-1. Concentrations at 48 hours were 20 and 30 nM; concentrations at 7 days 10 and 3 nM.