Table 3.
| Exposure status |
XPC diplotypes
|
|||
|---|---|---|---|---|
| All other diplotypes combined
|
CC-CC diplotype
|
|||
| Case/control | OR (95%CI) * | Case/control | OR (95%CI) * | |
| Never smokers | 383/418 | 1.0 (reference) | 103/80 | 1.4 (1.0–1.9) |
| Former smokers † | 307/333 | 1.0 (0.8–1.2) | 63/63 | 1.1 (0.7–1.6) |
| Current smokers † | 174/179 | 1.1 (0.9–1.5) | 30/28 | 1.2 (0.7–2.1) |
| Never smokers | 383/419 | 1.0 (reference) | 103/80 | 1.4 (1.0–1.9) |
| < 15 pack-years smokers † | 121/91 | 1.5 (1.1–2.0) | 20/16 | 1.4 (0.7–2.7) |
| 15+ pack-years smokers † | 138/100 | 1.5 (1.1–2.0) | 34/10 | 3.7 (1.8–7.6) |
| PAH-DNA adducts | ||||
| Non detectable | 185/244 | 1.0 (reference) | 38/46 | 1.1 (0.7–1.8) |
| Detectable | 521/548 | 1.3 (1.0–1.6) | 118/98 | 1.6 (1.1–2.2) ‡ |
| Non detectable | 185/244 | 1.0 (reference) | 38/46 | 1.1 (0.7–1.8) |
| Detectable (below median) | 262/269 | 1.3 (1.0–1.7) | 67/53 | 1.7 (1.1–2.5) |
| Detectable (median and above) | 259/279 | 1.2 (0.9–1.6) | 51/45 | 1.5 (0.9–2.3) |
*
adjusted for age at reference.
†
total number of smokers <15 pack-years and 15+ pack-years less than that of former and current smokers are due to missing data for cigarettes per day or smoked years.
‡
P interaction = 0.69.