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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Eur J Pharm Sci. 2008 Jan 31;33(4-5):371–379. doi: 10.1016/j.ejps.2008.01.006

Figure 3.

Figure 3

Mean (± S.D.) plasma concentration profiles in guinea pigs after topical application of a gel formulation containing either CB-NTXOL-BUPOH (n = 6) or 6-β-naltrexol (control, n = 5). The dotted line (----) indicates the plasma concentration obtained after the removal of the formulation.