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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Eur J Pharm Sci. 2008 Jan 31;33(4-5):371–379. doi: 10.1016/j.ejps.2008.01.006

Table 3.

Sensitization potential of p-phenylenediamine and 6-β-naltrexol in hairless guinea pigs.

Group Response grade Incidence Severity

0 0.5 1 2 3
p-Phenylenediamine Control 0 5 0 0 0 0/5 0.8
Test 0 1 4 5 0 9/10 2.65
NTXOL Control 5 0 0 0 0 0/5 0
Test 5 0 0 0 0 0/5 0