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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Am J Obstet Gynecol. 2008 Apr;198(4):471.e1–471.e8. doi: 10.1016/j.ajog.2008.01.009

Figure 4. Cytotrophoblast apoptosis after H/R is rescued by recombinant HBEGF signaling through its cognate receptors, HER1 and HER4.

Figure 4

TUNEL was determined as in Fig. 2B for cytotrophoblast cells cultured under the indicated O2 treatment regimes with or without addition of 1 nM recombinant HBEGF, or 10 µM of blocking antibodies against HER1 and HER4, as shown on the × axis. *, p< 0.05 compared to control (Normoxia no Ab).