Table 1.

Patients given DDAVP during treatment for hyponatremia^a

Patient	Age (yr)/Gender	Causative Factors of Hyponatremia	Precorrection PNa (mmol/L)	Rx With 3% NaCl	ΔPNa before DDAVP (mmol/L)	Time of DDAVP from Precorrection PNa (h)	Correction Rate before DDAVP (mmol/L per h)	Urine Output before DDAVP (ml/h)	UOsm before DDAVP (mOsm/kg)	ΔPNa at 24 h (mmol/L)	ΔPNa at 48 h (mmol/L)
Group 1
1	44/F	PSYCH	122	No	16	21	2.28	353	199	16	17
2	60/F	SSRI, THZ, ALC	115b	No	20	24	1.08	425	106	20	20
3	79/F	HYPOVOL	109	No	12	16	0.78	–	63	12	12
4	68/F	SSRI, THZ	108	No	17	17	0.83	–	191	17	16
5	24/F	POST-OP, N&V	129	No	13	14	1.55	–	–	13	13
6	65/F	ALC	112b	No	13	23	1.56	–	254	13	13
Group 2
7	42/M	SSRI, ALC	115b	No	6	5	1.26	302	72	7	7
8	66/F	SCCL	110	No	7	5	1.53	148	342	9	14
9	78/M	SSRI, THZ	111	Yes	1	8	0.18	266	284	7	17
10	34/F	HYPOVOL, ARF	124	No	3	4	2.61	2796	340	7	16
11	59/F	ALC, HYPOVOL	106	Yes	10	24	0.75	–	323	10	17
12	77/F	COPD, POLYDIP, THZ	116	Yes	9	13	1.48	237	–	9	9
13	81/F	SSRI, PNEUM	110	Yes	7	10	2.00	300	228	9	16
14	87/F	TRICYC, NSAID	116	No	6	11	1.00	419	–	9	9
15	48/F	COPD, PNEUM	110b	Yes	6	18	0.57	93	457	8	16
16	63/F	SSRI, CARB, PSYCH	117	No	6	4	1.50	270	83	12	15
17	61/F	PSYCH, SSRI	118	No	11	23	1.00	378	163	11	14
18	67/F	SSRI, HYPOVOL	120	No	4	8	1.00	225	140	8	15
19	54/F	COPD, HYPOX	117	No	11	12	0.96	–	397	11	15
20	84/M	THZ, ARF	120	No	6	10	1.62	380	308	8	8

^aALC, acute alcoholism and alcohol withdrawal; ARF, acute renal failure; CARB, carbamazepine; COPD, chronic obstructive pulmonary disease exacerbation; DDAVP, desmopressin acetate; HYPOVOL, hypovolemia; HYPOX, hypoxemia; NSAID, nonsteroidal anti-inflammatory drug; N&V, nausea and vomiting; PNa, plasma sodium concentration; PNEUM, pneumonia; POLYDIP, polydipsia; POST-OP, postoperative; PSYCH, psychosis with self-induced water intoxication; SCCL, small cell carcinoma of the lung; SSRI, selective serotonin reuptake inhibitor; THZ, thiazide diuretic; TRICYC, tricyclic antidepressant.

^bSeizure associated with precorrection PNa.