Table 1.
Main clinical, biochemical, vascular, and echocardiographic data in the original study cohort and in patients who repeated the Echo-Color Doppler study of the carotid arteries
| Original Cohort (n = 135) | Patients Who Repeated Echo-Color Doppler Study (n = 103)
|
P (second vs first visit) | ||
|---|---|---|---|---|
| First Visit | Second Visit | |||
| Age, yr | 60.0 ± 16.0 | 58.1 ± 15.8 | 59.4 ± 15.8 | <0.001 |
| BMI, kg/m2 | 25.1 ± 4.4 | 24.7 ± 4.1 | 24.6 ± 4.2 | 0.79 |
| Males, n (%) | 79 (58) | 61 (59) | 61 (59) | 1.00 |
| Diabetics, n (%) | 19 (14) | 12 (12) | 12 (12) | 1.00 |
| Smokers, n (%) | 66 (49) | 50 (48) | 50 (48) | 1.00 |
| Patients on antihypertensive therapy, n (%) | 77 (57) | 62 (60) | 62 (60) | 1.00 |
| Systolic pressure, mmHg | 135 ± 21 | 136 ± 22 | 135 ± 24 | 0.62 |
| Diastolic pressure, mmHg | 75 ± 13 | 76 ± 13 | 74 ± 14 | 0.09 |
| Pulse pressure, mmHg | 60 ± 16 | 60 ± 16 | 61 ± 17 | 0.53 |
| Heart rate, beats/min | 83 ± 13 | 83 ± 13 | 82 ± 11 | 0.72 |
| Hemoglobin, g/L) | 105 ± 20 | 104 ± 18 | 103 ± 15 | 0.48 |
| Albumin, g/L | 38 ± 6 | 39 ± 6 | 38 ± 5 | 0.31 |
| Cholesterol, mg/dl | 5.46 ± 1.41 | 5.40 ± 1.32 | 4.40 ± 1.05 | <0.001 |
| Calcium * phosphate, mMol2/L2 | 4.44 ± 1.33 | 4.50 ± 1.31 | 4.35 ± 1.30 | 0.33 |
| C-reactive protein, mg/L | 8.4 (3.4–19.1) | 7.6 (3.4–16.0) | NA | — |
| Homocysteine, μMol/L | 28.0 (20.5–42.8) | 27.7 (20.7–43.9) | NA | — |
| Fibrinogen, mg/dl | 567 (476–675) | 567 (477–690) | NA | — |
| LVMI, g/m2.7 | 69.8 ± 19.0 | 67.3 ± 17.0 | 72.7 ± 20.9 | <0.001 |
| Intima media thickness, mm | 1.04 ± 0.23 | 1.02 ± 0.22 | 1.01 ± 0.20 | 0.24 |
| CCAD, mm | 6.88 ± 0.92 | 6.86 ± 0.92 | 6.86 ± 0.93 | 0.98 |
| CSA, mm2 | 12.1 ± 3.4 | 11.9 ± 3.4 | 11.8 ± 3.2 | 0.25 |
| CCAwlr | 0.32 ± 0.08 | 0.30 ± 0.07 | 0.30 ± 0.06 | 0.21 |
| No. of atherosclerotic plaques | 3 (1–5) | 3 (0–5) | 4 (1–6) | <0.001 |
| No. of patients with atherosclerotic plaques | ||||
| 0 | 29 (21%) | 26 (25%) | 19 (18%) | — |
| 1–4 | 66 (49%) | 51 (50%) | 39 (38%) | <0.001 |
| >4 | 40 (30%) | 31 (25%) | 45 (44%) | — |
NA, not available; LVMI, left ventricular mass index; CCAD, common carotid artery diameter; CCAwlr, common carotid artery wall to lumen ratio; CSA, cross-sectional area.