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Bmp4 promoter activity during glomerular development in Bmp4 +/− mice. (A and C) Background lacZ staining in wild-type mice at E15.5 (A) or P0 (C). (B) In Bmp4 +/− mice, lacZ driven by Bmp4 promoter was first detected in future podocytes and Bowman's epithelial cells at S-shaped stage (SB) and capillary loop stage (CP) at E15.5. (D) Only background LacZ staining was detected in mature glomeruli at P0. Magnification, ×400.
