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Immunohistologic analysis of Nephrin-Bmp4 mice. Immunostaining for WT-1 (A and B), CD31 (C and D), or desmin (E and F) in glomeruli from wild-type (A, C, and E) and Nephrin-Bmp4 (B, D, and F) mice. Most cells in the abnormal glomeruli of Nephrin-Bmp4 mice were WT-1–positive cells (B). Only a few CD31-positive cells (D) or desmin-positive cells (F) were present in glomeruli from Nephrin-Bmp4 mice. Magnification, 400.
