Table 5.

Effect of the CYP4F2 regulatory haplotypes on BP and risk factors for hypertension^a

Parameter	Hap I/Hap I (n = 419)	Hap I/Hap II (n = 123)	Hap II/Hap II (n = 5)	Pb	Pc	Pd
SBP (mmHg)	131.64 ± 23.00	128.02 ± 23.77	126.00 ± 20.43	0.282	0.644	0.114
DBP (mmHg)	84.35 ± 13.56	81.52 ± 13.18	82.00 ± 10.37	0.118	0.778	0.039
MAP (mmHg)	108.00 ± 17.10	104.77 ± 17.04	104.00 ± 15.27	0.168	0.671	0.059
BMI (kg/m2)	23.02 ± 4.26	23.61 ± 4.64	25.19 ± 7.32	0.246	0.301	0.164
Total cholesterol (mmol/L)	4.60 ± 1.06	4.65 ± 1.11	4.68 ± 0.92	0.912	0.889	0.671
Triglycerides (mmol/L)	1.32 ± 1.24	1.23 ± 0.90	1.27 ± 0.83	0.766	0.952	0.467
LDL cholesterol (mmol/L)	2.72 ± 0.81	2.70 ± 0.88	2.77 ± 0.61	0.952	0.882	0.805

^aData are means ± SD. MAP, mean arterial pressure.

^bIn an additive model.

^cIn a dominant model for Hap I.

^dIn a recessive model for Hap I.