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Immunoblots of caspase-7, Bcl-2, and Bax proteins. Full-length caspase-7 protein expression (35 kDa) in the kidney was increased in cpk, cpk;casp3+/−, and cpk;casp3−/− mice compared with +/+ mice. Anti-apoptotic Bcl-2 protein (26 kDa) expression was decreased in cpk, cpk;casp3+/−, and cpk;casp3−/− mice compared with +/+. Pro-apoptotic Bax protein (23 kDa) expression was unchanged. Representative immunoblots of at least 3 separate experiments.
