Table 1.
Patient demographics and baseline laboratory values
| Characteristica | Conventional Care (n = 184) | Cinacalcet (n = 368) |
|---|---|---|
| Sex, n (%) | ||
| male | 117 (64) | 224 (61) |
| female | 67 (36) | 144 (39) |
| Race, n (%)b | ||
| white | 172 (93) | 349 (95) |
| black and other | 12 (7) | 14 (3) |
| Age, years | ||
| mean (SD) | 58.3 (14.5) | 58.5 (14.5) |
| range | 24 to 84 | 20 to 89 |
| Duration of dialysis, months mean (SD) | 69.4 (73.6) | 64.1 (72.1) |
| Dialysis type, n (%) | ||
| hemodialysis | 151 (82) | 285 (77) |
| hemodiafiltration | 28 (15) | 59 (16) |
| hemofiltration | 0 | 3 (1) |
| peritoneal dialysis | 5 (3) | 21 (6) |
| Vitamin D use, n (%) | 126 (68) | 252 (68) |
| Phosphate binder use, % | 90 | 92 |
| calcium-based | 41 | 48 |
| sevelamer HCl | 54 | 52 |
| aluminum-based | 20 | 19 |
| iPTH, mean (SD), pg/ml | 507 (143) | 505 (147) |
| Ca × P, mean (SD) mg2/dl2 | 52.5 (15.4) | 53.6 (16.4) |
| ≤55 mg2/dl2, n (%) | 113 (61) | 227 (62) |
| >55 mg2/dl2, n (%) | 71 (39) | 141 (38) |
| Serum calcium, mean (SD), mg/dl | 9.7 (0.8) | 9.7 (0.8) |
| Serum phosphorus, mean (SD), mg/dl | 5.4 (1.5) | 5.5 (1.7) |
a
No statistically significant differences between the two groups in any baseline demographic or laboratory value comparison.
b
Race information was lacking for five patients in the cinacalcet group.