Table 2.
Comparison of α-galactosidase activity assayed from healthy individuals in the presence and absence of GalNAc inhibitora
| Parameter | Total α-Galactosidase (Assayed without Inhibitor) | α-Galactosidase A (Assayed with 100 mM GalNAc) | α-Galactosidase B (by subtraction) | α-Galactosidase B as % of Total |
|---|---|---|---|---|
| Plasma (nmol/h per ml plasma; n = 20 individuals) | ||||
| mean | 5.3 | 5.0 | 0.3 | 6.0 |
| median | 5.3 | 4.9 | 0.3 | 6.1 |
| observed range | 3.4 to 7.1 | 3.1 to 7.0 | 0.0 to 1.0 | 0.0 to 18.1 |
| Leucocytes (nmol/h per mg protein; n = 30 individuals) | ||||
| mean | 81.7 | 79.3 | 2.3 | 2.8 |
| median | 77.3 | 77.7 | 2.0 | 3.0 |
| observed range | 49.9 to 126.3 | 47.2 to 124.3 | 0.0 to 8.0 | 0.0 to 7.6 |
a
GalNAc, N-acetylgalactosamine.