Table 5.
Association of cumulative mean predialysis serum β2M levels during follow-up with cardiac mortality or infectious mortalitya
| Parameter | n | Cardiac Mortality
|
Infectious Mortality
|
||||
|---|---|---|---|---|---|---|---|
| HR (per 10-mg/L Increase) | 95% CI | P | HR (per 10-mg/L Increase) | 95% CI | P | ||
| Entire cohort | 1813 | 1.10 | 0.99 to 1.21 | 0.079 | 1.21 | 1.07 to 1.37 | 0.002 |
| Subgroup with ≤3.7 yr of dialysis | 1244 | 1.08 | 0.93 to 1.24 | 0.31 | 1.22 | 1.03 to 1.45 | 0.023 |
| Subgroup with >3.7 yr of dialysis | 569 | 1.10 | 0.93 to 1.30 | 0.26 | 1.24 | 1.00 to 1.54 | 0.050 |
a
Adjusted for baseline age, gender, race, diabetes, years on dialysis, kinetically modeled urea distribution volume, comorbidity index, serum albumin level, residual kidney urea clearance, dialyzer flux, and ultrafiltration volume normalized by body weight.