Table 3.
Clearance of indican and PCS in PD patientsa
| Parameter | RRF | NRRF |
|---|---|---|
| Indican | ||
| plasma total (mg/dl) | 1.8 ± 1.3 | 3.4 ± 1.4b |
| plasma unbound (%) | 7 ± 3 | 8 ± 2 |
| removal rate (mg/d) | 45 ± 17 | 25 ± 16b |
| CPD (ml/min) | 0.3 ± 0.1 | 0.5 ± 0.2b |
| CRenal (ml/min) | 2.7 ± 2.5 | 0.0 ± 0.0b |
| CTotal (ml/min) | 3.0 ± 2.5 | 0.5 ± 0.2b |
| D/P (unbound) | 0.6 ± 0.2 | 0.7 ± 0.2 |
| PCS | ||
| plasma total (mg/dl) | 2.7 ± 1.6 | 2.6 ± 1.3 |
| plasma unbound (%) | 5 ± 2 | 7 ± 2b |
| removal rate (mg/d) | 49 ± 34 | 14 ± 6b |
| CPD (ml/min) | 0.3 ± 0.1 | 0.4 ± 0.2b |
| CRenal (ml/min) | 1.3 ± 1.0 | 0.0 ± 0.0b |
| CTotal (ml/min) | 1.6 ± 1.0 | 0.4 ± 0.2b |
| D/P (unbound) | 0.7 ± 0.2 | 0.7 ± 0.3 |
a
Data are means ± SD. D/P (unbound), ratio of dialysate solute concentration to unbound plasma solute concentration; PCS, p-cresol sulfate.
b
P < 0.05 RRF versus NRRF.