Table 2.
Comparison of the effects of sevelamer and calcium acetate on the parametera
| Sevelamer (n = 25)
|
Calcium Acetate (n = 25)
|
|||
|---|---|---|---|---|
| BT | AT | BT | AT | |
| Fetuin-A (g/L) | 0.27 (0.23 to 0.34) | 0.35 (0.24 to 0.43)b | 0.27 (0.24 to 0.31) | 0.28 (0.21 to 0.33) |
| FMD (%) | 6.0 (4.3 to 6.8) | 6.8 (5.5 to 8.8)b | 5.8 (4.7 to 7.0) | 6.0 (4.4 to 7.0) |
| LDL cholesterol (mg/dl) | 113.5 ± 16.0 | 103.7 ± 17.0b | 117.8 ± 19.2 | 123.2 ± 15.8 |
| Serum albumin (g/dl) | 3.9 ± 0.3 | 4.0 ± 0.4 | 3.9 ± 0.3 | 3.8 ± 0.3 |
| hsCRP (mg/L) | 15 (9 to 18) | 10 (5 to 14)b | 14 (10 to 24) | 14 (7 to 21) |
| iPTH (pg/ml) | 155 (120 to 183) | 164 (117 to 232)b | 148 (148 to 186) | 176 (123 to 253)b |
| Serum Ca (mg/dl) | 8.1 ± 0.4 | 7.9 ± 0.5 | 8.0 ± 0.4 | 8.2 ± 0.3 |
| Serum PO4(mg/dl) | 7.8 ± 0.6 | 5.9 ± 0.9b | 7.8 ± 0.7 | 6.0 ± 0.7b |
| Ca × PO4 product | 62 (54 to 73) | 48.0 (29.6 to 59.5)b | 63 (46 to 71) | 48.0 (39.1 to 60.2)b |
a
Data are mean± SD and median. Paired samples t test.
b
P < 0.001