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. 2008 Jan;3(1):98–104. doi: 10.2215/CJN.03330807

Table 4.

Full model and final model for hemoglobin variation

Parameter Model with All Parameters
Final Model
Coef. 95% CI P Coef. 95% CI P
Epo dose (per 10,000 units/month) −0.18 −0.28 to −0.09 <0.0001 −0.18 −0.26 to −0.10 <0.0001
Epo dose × time 0.05 0.01 to 0.10 0.01 0.04 0.01 to 0.07 <0.01
Serum albumin (g/dl) 0.78 0.15 to 1.41 0.02 0.73 0.18 to 1.28 0.01
Albumin × time 0.41 0.03 to 0.79 0.03 0.49 0.14 to 0.84 <0.01
WBC count (n/1000/ml) 0.12 0.01 to 0.23 0.03
Iron dose (per 100 mg/month) −0.04 −0.13 to 0.04 0.3
Iron dose × time 0 −0.00 to 0.00 0.1
Post dialysis weight (kg) −0.01 −0.03 to 0.00 0.1
WBC count × time −0.03 −0.08 to 0.02 0.2
Plasma malonaldehyde (mmol/L) 0.02 −0.09 to 0.13 0.7
Malonaldehyde × time 0.01 −0.04 to 0.07 0.6
log Plasma MCP1 (ng/ml) 0.07 −0.31 to 0.45 0.7
log Plasma MCP1 × time −0.14 −0.32 to 0.05 0.2
Serum iron 0 −0.00 to 0.00 0.5
Serum iron × time 0 −0.00 to 0.00 0.7
Log serum ferritin −0.31 −0.69 to 0.06 0.1
Log ferritin × time 0.1 −0.02 to 0.22 0.1
Total iron binding capacity 0 −0.01 to 0.01 0.9
Total iron binding capacity × time 0 −0.00 to 0.00 0.9
Constant 14.82 11.40 to 18.23 <0.0001 12.6 12.2 to 13.0 <0.0001
Random Effects
    SD Intercept 0.6 1.53
        SD Time 1.63 0.59
    Corr (intercept, time) −0.49 −0.46
    SD Residual 0.76 0.84
        LL −442 −519.8

Albumin is centered at 4 g/dl and white blood cell (WBC) count at 4000/μl.