Table 4.
Parameter | Model with All Parameters
|
Final Model
|
||||
---|---|---|---|---|---|---|
Coef. | 95% CI | P | Coef. | 95% CI | P | |
Epo dose (per 10,000 units/month) | −0.18 | −0.28 to −0.09 | <0.0001 | −0.18 | −0.26 to −0.10 | <0.0001 |
Epo dose × time | 0.05 | 0.01 to 0.10 | 0.01 | 0.04 | 0.01 to 0.07 | <0.01 |
Serum albumin (g/dl) | 0.78 | 0.15 to 1.41 | 0.02 | 0.73 | 0.18 to 1.28 | 0.01 |
Albumin × time | 0.41 | 0.03 to 0.79 | 0.03 | 0.49 | 0.14 to 0.84 | <0.01 |
WBC count (n/1000/ml) | 0.12 | 0.01 to 0.23 | 0.03 | |||
Iron dose (per 100 mg/month) | −0.04 | −0.13 to 0.04 | 0.3 | |||
Iron dose × time | 0 | −0.00 to 0.00 | 0.1 | |||
Post dialysis weight (kg) | −0.01 | −0.03 to 0.00 | 0.1 | |||
WBC count × time | −0.03 | −0.08 to 0.02 | 0.2 | |||
Plasma malonaldehyde (mmol/L) | 0.02 | −0.09 to 0.13 | 0.7 | |||
Malonaldehyde × time | 0.01 | −0.04 to 0.07 | 0.6 | |||
log Plasma MCP1 (ng/ml) | 0.07 | −0.31 to 0.45 | 0.7 | |||
log Plasma MCP1 × time | −0.14 | −0.32 to 0.05 | 0.2 | |||
Serum iron | 0 | −0.00 to 0.00 | 0.5 | |||
Serum iron × time | 0 | −0.00 to 0.00 | 0.7 | |||
Log serum ferritin | −0.31 | −0.69 to 0.06 | 0.1 | |||
Log ferritin × time | 0.1 | −0.02 to 0.22 | 0.1 | |||
Total iron binding capacity | 0 | −0.01 to 0.01 | 0.9 | |||
Total iron binding capacity × time | 0 | −0.00 to 0.00 | 0.9 | |||
Constant | 14.82 | 11.40 to 18.23 | <0.0001 | 12.6 | 12.2 to 13.0 | <0.0001 |
Random Effects | ||||||
SD Intercept | 0.6 | 1.53 | ||||
SD Time | 1.63 | 0.59 | ||||
Corr (intercept, time) | −0.49 | −0.46 | ||||
SD Residual | 0.76 | 0.84 | ||||
LL | −442 | −519.8 |
Albumin is centered at 4 g/dl and white blood cell (WBC) count at 4000/μl.