Table 2.

Histologic analysis of remnant kidney tissue after 8 wk of treatment^a

Group	n	Glomerular Cross-Sectional Area (104 μm2)	Glomerular Damage (Score)	Tubulointerstitial Damage (Score)
Sham	6	0.90 ± 0.18	0.15 ± 0.11	0.10 ± 0.21
Nephrectomy	5	1.96 ± 0.39b	1.63 ± 0.75b	1.89 ± 0.65b
CLO	5	1.49 ± 0.24b,c	1.29 ± 0.22c	0.93 ± 0.43b,c
IRB	5	1.36 ± 0.31bc	0.98 ± 0.31c	0.89 ± 0.32bc
CLO/IRB	6	1.03 ± 0.38c,d	0.59 ± 0.21c,d,e	0.41 ± 0.35c,d,e

^aData are means ± SD. CLO, clopidogrel; IRB, irbesartan; CLO/IRB, CLO plus IRB.

^bP < 0.05 versus sham.

^cP < 0.05 versus nephrectomy.

^dP < 0.05 versus CLO.

^eP < 0.05 versus IRB.