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. 2008 Apr 29;98(9):1525–1532. doi: 10.1038/sj.bjc.6604318

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Copyright © 2008 Cancer Research UK

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Influence of anhydrotetracycline (ATc) and trastuzumab on tumour development in nude mice. As soon as tumours reached a mean diameter of 1.5–1.8 cm (corresponding to 1.7–2.0 cm³) mice received daily injections of anhydrotetracycline (ATc) and trastuzumab (onset of therapy is day 0). Data are mean values and s.e. of 3–5 mice per group. A tumour volume of 100% corresponds to 1.7–2.0 cm³.