Table 2. Risk of lung cancer, other smoking-related cancers, and cardiovascular disease distributed by demographic and lifestyle factorsa.
Controlsb
|
Lung Cancer
|
Smoking-related cancerb
|
Cardiovascular diseasec
|
|||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Male | Female |
Male
|
Female
|
Male
|
Female
|
Male
|
Female
|
|||||||||||||||||||
n=1383 | n=2676 |
n=333
|
95% CI
|
n=90
|
95% CI
|
n=1330
|
95% CI
|
n=2631
|
95% CI
|
n=159
|
95% CI
|
n=557
|
95% CI
|
|||||||||||||
Risk factor | n | n | n | OR | LCI | UCI | n | OR | LCI | UCI | n | OR | LCI | UCI | n | OR | LCI | UCI | n | OR | LCI | UCI | n | OR | LCI | UCI |
Age | ||||||||||||||||||||||||||
18–34 | 253 | 412 | 5 | 1.0 | Referent | 2 | 1.0 | Referent | 90 | 1.0 | Referent | 213 | 1.0 | Referent | 22 | 1.0 | Referent | 77 | 1.0 | Referent | ||||||
35–54 | 478 | 1212 | 136 | 12.5 | 5.0 | 31.4 | 27 | 2.8 | 0.6 | 12.1 | 530 | 2.4 | 1.8 | 3.3 | 1283 | 1.5 | 1.2 | 1.8 | 88 | 2.0 | 1.2 | 3.4 | 228 | 0.8 | 0.6 | 1.1 |
55–98 | 650 | 1050 | 192 | 15.4 | 6.1 | 38.7 | 61 | 7.1 | 1.7 | 30.3 | 710 | 2.5 | 1.9 | 3.4 | 1134 | 1.4 | 1.1 | 1.7 | 49 | 0.8 | 0.4 | 1.5 | 252 | 1.0 | 0.7 | 1.4 |
χ2 (P trend) | 35.0 | (<0.0001) | 19.2 | (<0.0001) | 23.2 | (<0.0001) | 2.7 | (0.10) | 2.1 | (0.15) | 0.5 | (0.50) | ||||||||||||||
Unspecified | 2 | 2 | 0 | — | — | — | 0 | — | — | — | 0 | — | — | — | 1 | — | — | — | 0 | — | — | — | 0 | — | — | — |
Education (years) | ||||||||||||||||||||||||||
0–5 | 761 | 1317 | 226 | 1.0 | Referent | 61 | 1.0 | Referent | 848 | 1.0 | Referent | 1683 | 1.0 | Referent | 66 | 1.0 | Referent | 287 | 1.0 | Referent | ||||||
6–8 | 371 | 888 | 87 | 0.9 | 0.7 | 1.2 | 27 | 1.1 | 0.7 | 1.8 | 352 | 0.9 | 0.8 | 1.1 | 728 | 0.8 | 0.7 | 0.9 | 45 | 1.2 | 0.8 | 1.9 | 201 | 1.1 | 0.9 | 1.4 |
9+ | 243 | 462 | 19 | 0.5 | 0.3 | 0.8 | 2 | 0.3 | 0.1 | 1.2 | 121 | 0.7 | 0.5 | 0.9 | 189 | 0.5 | 0.4 | 0.6 | 27 | 1.2 | 0.7 | 2.1 | 67 | 0.7 | 0.5 | 1.0 |
χ2 (P trend) | 5.4 | (0.02) | 1.3 | (0.26) | 4.6 | (0.03) | 59.8 | (<0.0001) | 0.7 | (0.41) | 1.4 | (0.24) | ||||||||||||||
Unspecified | 8 | 9 | 1 | 0.8 | 0.1 | 8.0 | 0 | — | — | — | 9 | 1.6 | 0.6 | 4.8 | 31 | 3.1 | 1.5 | 6.6 | 21 | 6.1 | 1.0 | 36.4 | 2 | 1.1 | 0.2 | 5.1 |
Smoking status d | ||||||||||||||||||||||||||
Never | 528 | 2264 | 16 | 1.0 | Referent | 46 | 1.0 | Referent | 176 | 1.0 | Referent | 1970 | 1.0 | Referent | 25 | 1.0 | Referent | 412 | 1.0 | Referent | ||||||
Former | 338 | 167 | 83 | 7.2 | 4.1 | 12.6 | 12 | 2.6 | 1.3 | 5.1 | 344 | 2.8 | 2.2 | 3.5 | 235 | 1.4 | 1.1 | 1.8 | 23 | 1.6 | 0.9 | 2.8 | 82 | 2.6 | 1.9 | 3.4 |
Current | 513 | 227 | 234 | 16.3 | 9.6 | 27.6 | 32 | 6.4 | 4.0 | 10.4 | 808 | 4.6 | 3.7 | 5.7 | 407 | 1.9 | 1.6 | 2.2 | 90 | 3.4 | 2.1 | 5.4 | 63 | 1.5 | 1.1 | 2.1 |
χ2 (P trend) | 142.4 | (<0.0001) | 58.2 | (<0.0001) | 189.0 | (<0.0001) | 50.5 | (<0.0001) | 29.3 | (<0.0001) | 15.0 | (<0.0001) | ||||||||||||||
Ever | 851 | 394 | 317 | 12.2 | 7.3 | 20.6 | 44 | 4.6 | 3.0 | 7.2 | 1152 | 3.9 | 3.2 | 4.7 | 642 | 1.7 | 1.4 | 1.9 | 113 | 2.7 | 1.7 | 4.3 | 145 | 2.0 | 1.6 | 2.5 |
Unspecified | 4 | 18 | — | — | — | 0 | — | — | — | 2 | 2.0 | 0.3 | 13.0 | 19 | 1.1 | 0.6 | 2.2 | 15.3 | 2.1 | 111.7 | 0 | — | — | — | ||
Cooking fuel e | ||||||||||||||||||||||||||
Electrical | 1079 | 1970 | 230 | 1.0 | Referent | 60 | 1.0 | Referent | 937 | 1.0 | Referent | 1588 | 1.0 | Referent | 104 | 1.0 | Referent | 432 | 1.0 | Referent | ||||||
Non-electrical | 300 | 703 | 103 | 1.6 | 1.2 | 2.2 | 30 | 1.4 | 0.8 | 2.2 | 390 | 1.5 | 1.3 | 1.9 | 1030 | 1.6 | 1.4 | 1.8 | 34 | 1.2 | 0.8 | 1.8 | 125 | 0.8 | 0.6 | 1.0 |
χ2 (P heterogeneity) | 10.1 | (0.002) | 1.6 | (0.20) | 19.4 | (<0.0001) | 59.6 | (<0.0001) | 0.5 | (0.47) | 3.7 | (0.05) | ||||||||||||||
Unspecified | 4 | 3 | 0 | — | — | — | 0 | — | — | — | 3 | 0.6 | 0.1 | 3.4 | 13 | 5.1 | 1.4 | 18.3 | 21 | 5.1 | 0.7 | 37.2 | 0 | — | — | — |
Smoking status by cooking fuel | ||||||||||||||||||||||||||
Never smoke/electrical | 397 | 1662 | 11 | 1.0 | Referent | 31 | 1.0 | Referent | 113 | 1.0 | Referent | 1178 | 1.0 | Referent | 17 | 1.0 | Referent | 326 | 1.0 | Referent | ||||||
Never smoke/non-electrical | 131 | 600 | 5 | 1.4 | 0.5 | 4.0 | 15 | 1.3 | 0.7 | 2.4 | 63 | 1.6 | 1.1 | 2.4 | 782 | 1.6 | 1.4 | 1.8 | 8 | 1.5 | 0.6 | 3.6 | 86 | 0.7 | 0.5 | 0.9 |
Ever smoke/electrical | 681 | 293 | 219 | 11.1 | 6.0 | 20.8 | 29 | 4.3 | 2.5 | 7.3 | 824 | 3.9 | 3.1 | 5.0 | 399 | 1.7 | 1.4 | 2.0 | 87 | 3.0 | 1.8 | 5.2 | 106 | 1.8 | 1.4 | 2.3 |
Ever smoke/non-electrical | 167 | 101 | 98 | 20.1 | 10.4 | 38.9 | 15 | 6.8 | 3.5 | 13.4 | 326 | 6.1 | 4.6 | 8.2 | 241 | 2.7 | 2.1 | 3.5 | 26 | 3.6 | 1.8 | 7.0 | 39 | 1.9 | 1.3 | 2.9 |
χ2 (P trend) | 117.8 | (<0.0001) | 44.6 | (<0.0001) | 188.0 | (<0.0001) | 91.6 | (<0.0001) | 18.1 | (<0.0001) | 17.9 | (<0.0001) | ||||||||||||||
Unspecified | 7 | 20 | 0 | — | — | — | 0 | — | — | — | 4 | 2.0 | 0.5 | 7.5 | 31 | 2.0 | 1.1 | 3.6 | 21 | 15.8 | 4.0 | 62.1 | 0 | — | — | — |
Analyses adjusted for age, education, smoking status, and cooking fuel; odds ratios (OR) with 95% lower (LCI) and upper (UCI) confidence intervals presented.
See Table 1 for disease groupings.
Primarily hypertenstion (37%), stroke (25%) and congestive heart failure (18%).
Current smokers included those who smoked within 5 years of interview.
Non-electrical cooking fuel included wood, charcoal, coal, anthracite, parafin, and gas.