Table 2. Univariate analysis of prognostic factors for OS.

Covariate	n	Hazard ratio	95% CI	P-value for OS
Age (years)
<70	54	0.984	0.448–2.160	0.968
⩾70	15
Gender
Male	58	0.456	0.161–1.291	0.139
Female	11
Effect of CRT
Effective	49	0.207	0.104–0.413	0.0001***
Not effective	20
Lymph-node metastasis
Positive	31	3.567	1.751–7.266	0.0001***
Negative	38
Distant metastasis
Positive	13	4.064	2.016–8.192	0.0001***
Negative	56
Depth of tumour invasion
T3	40	0.383	0.195–0.751	0.005*
T4	29
Tumour location a
Upper	10	1.139	0.442–2.934	0.787
Lower	59
Gli-1 expression
Nuclear	7	4.115	1.676–10.104	0.002**
Others	62

CI=confidence interval; CRT=chemoradiotherapy; Gli-1=glioma-associated oncogene homologue 1; OS=overall survival.

^*P<0.01; ^**P<0.005; ^***P<0.0005.

^aUpper or lower, above or below the tracheal bifurcation.