Figure 2.

Total parasite densities were lower during IL-10R blockade, regardless of P. c. chabaudi parasite genotype. Line graphs represent the dynamics of total parasite density in αIL-10R (filled symbols) or control IgG (open symbols) treated mice during single-clone infections with each of eight P. c. chabaudi clones. Each line represents the mean of five mice (± S.E.), except where deaths had occurred. Regardless of P. c. chabaudi parasite genotype, neutralizing IL-10R resulted in lower total parasite densities between days 3 to 21 p.i. and lower early parasite densities (days 3–8 p.i.) compared to control mice.