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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Resuscitation. 2007 Dec 21;77(2):242–249. doi: 10.1016/j.resuscitation.2007.10.015

Figure 1.

Figure 1

Schematic of experimental protocol. Thick horizontal lines show duration of arrest for each group, dark grey box represent CPR interval, and light grey area represents interval of therapeutic hypothermia. A, normothermic control group with 8 min arrest duration, approximately 3–4 min of CPR and 2 hrs of monitored recovery at 37°C. B, early intra-arrest (EIH) cooling group with 8 min arrest duration and 3–4 min CPR interval. In addition, cooling is initiated at 6.5 min of arrest such that resuscitation occurs at 30°C. After one hour, animals are rewarmed and monitored for 1 hour at 37°C. C, delayed intra-arrest (DIH) cooling group, with 9.5 min arrest duration and 3–4 min CPR interval. Cooling is initiated at 8 min of arrest such that resuscitation occurs at 30°C. After one hr, animals are rewarmed and monitored for an additional hr at 37°C.