Table 1.
Group characteristics (mean ± SD) during baseline, arrest and resuscitation periods; and at 120 min following initial resuscitation, n=15 per group. Significant differences between control and hypothermia groups (*) and between the hypothermia groups (EIH and DIH) are denoted (¥) for p-value < 0.05. Chest compression (CC) rate and duration; diastolic blood pressure (DBP) and ETCO2 were averaged over the first 2 min of resuscitation. Abbreviations: maximum left ventricular pressure (LVPmax), end-tidal CO2 (ETCO2), return of spontaneous circulation (ROSC), not applicable (NA).
| Control | EIH | DIH | ||
|---|---|---|---|---|
| Baseline | Weight | 29.5±2.0 | 29.2±1.4 | 29.0±1.5 |
| Temperature, °C | 36.4±0.3 | 36.4±0.4 | 36.5±0.4 | |
| Heart rate, bpm | 280.8±65.7 | 251.8±43.0 | 256.8±53.5 | |
| LVPmax, mmHg | 94.4±8.5 | 92.3±7.2 | 92.0±7.4 | |
| ETCO2, mmHg | 36.1±3.8 | 36.6±3.4 | 37.1±2.5 | |
| Arres | Cooling rate | NA | 5.1±1.9 | 5.3±1.8 |
| Warming rate | NA | 0.23±0.4 | 0.26±0.6 | |
| Resuscitation | ROSC, n (%) | 12 (80) | 14 (93) | 14 (93) |
| CC rate, bpm | 394±63.4 | 382±35.4 | 377±40.6 | |
| CC duration, s | 190.7±68.9 | 158.3±58.8 | 162.7±48.9 | |
| DBP, mmHg | 15.3±4.2 | 16.2±7.0 | 16.2±7.6 | |
| ETCO2, mmHg | 24.5±5.8 | 20.5±5.6* | 21.1±6.6* | |
| 120 min | Heart rate, bpm | 476.6±48.0 | 383.2±100.6 | 373.2±130.8 |
| LVPmax, mmHg | 60.1±10.2 | 80.2±8.6*¥ | 70.6±10.3* | |
| ETCO2, mmHg | 34.8±3.2 | 35.3±2.0 | 35.2±3.3 | |
| Survival, n (%) | 8 (53) | 14 (93) | 14 (93) | |