TABLE I.

Parameter Values Used in All Calculations

Parameter	Symbol	Value	Reference
Water dielectric	εw	80	Floris et al., 1991
Protein dielectric	εp	2	Gallicchio et al., 2000
Membrane core dielectric	εhc	2	Long et al., 2007
Lipid head group dielectric	εhg	80	Long et al., 2007
Equilibrium membrane width	L0	42 Å	Nielsen and Andersen, 2000
Head group width	Lhg	8 Å	Lipowsky and Sackman, 1995
Ion screening concentration	Ic	100 mM	Shrake and Rupley, 1973
Bulk interfacial surface tension	α	3 × 10−13 N/Å	Jacobs and White, 1989
Area compression-expansion modulus	Ka	1.425 × 10−11 N/Å	Jacobs and White, 1989
Bending or splay-distortion modulus	Kc	2.85 × 10−10 NÅ	Jacobs and White, 1989
α/Kc	γ	1.05 × 10−3 Å−2	Jacobs and White, 1989
2 Ka/(L02·Kc)	β	5.66 × 10−5 Å−4	Jacobs and White, 1989
SASA prefactor for nonpolar energy	a	0.028 kcal/mol·Å2	Gallicchio et al., 2000
Constant term for nonpolar energy	b	−1.7 kcal/mol	Gallicchio et al., 2000