Table 1.
Absolute Concentrations of Brain Metabolites Averaged Over Three Rat Pups 36 hr After the Onset of Focal Ischemia
| Metabolite |
Concentration (mmol/kg) |
|||
|---|---|---|---|---|
| Infarct region n = 5a | Edematous tissue n = 14 | Penumbra n = 13 | Contralateral hemisphere n = 13 | |
| Cr | 2.0 ± 1.2b | 2.1 ± 1.6 | 7.3 ± 1.0 | 7.6 ± 0.5 |
| NAA | 1.3 ± 0.8 | 1.5 ± 1.1 | 5.3 ± 0.9 | 5.9 ± 0.4 |
| Glu | 2.9 ± 1.1 | 2.5 ± 1.8 | 6.6 ± 1.1 | 7.0 ± 0.7 |
| Gln | 1.4 ± 0.8 | 1.3 ± 1.0 | 3.7 ± 0.6 | 2.8 ± 0.3 |
| Cho | 1.0 ± 0.5 | 0.4 ± 0.2 | 1.1 ± 0.3 | 1.3 ± 0.2 |
| Tau | 1.5 ± 1.4 | 2.6 ± 1.8 | 8.6 ± 1.4 | 9.4 ± 1.2 |
| Ins | — | 0.6 ± 0.5 | 2.3 ± 0.5 | 3.5 ± 0.4 |
| Glc | 1.1 ± 0.7 | 1.7 ± 1.1 | 4.4 ± 0.6 | 4.7 ± 0.8 |
| Lip (1.3 ppm) | 34 ± 24 | 49 ± 25 | 22 ± 19 | 14 ± 9 |
| Lac | 1.0 ± 0.6 | 0.7 ± 0.5 | 1.0 ± 0.7 | 0.9 ± 0.3 |
a
The number of voxels taken in statistics.
b
Arithmetic mean ± standard deviation.