Table 1.

Effect of extended infusion of carbapenem antibiotics

	Bactericidal cumulative reaction of response (%)a
Antibiotic regimen	30-minute infusion	3-hour infusion	Change (%)
Imipenem 1 g q8h	69.3	72.0	+2.7
Meropenem 1 g q8h	77.1	83.8	+6.7
Meropenem 2 g q8h	84.1	88.1	+4.0

Shown is the effect of extended infusion of carbapenem antibiotics on the bactericidal cumulative fraction of response against multidrug-resistant Pseudomonas aeruginosa [17]. ^aBactericidal exposure defined as 40% time above minimum inhibitory concentration. q8h, every 8 hours.