Figure 8. Effect of RNAi-mediated FoxO1 knockdown on hepatic gene expression.
Liver tissues collected from sacrificed C57BL/6J mice in control and RNAi treatment groups (n = 8 per group) were used for the preparation of total RNA. Hepatic mRNA levels of SREBP-1c (A), FAS (B), ACC (C), ACOX-1 (D), PPARα (E), and HNF4α (F) were determined using real-time quantitative RT-PCR. *P < 0.05 versus control.