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. 1999 Nov 9;96(23):13191–13196. doi: 10.1073/pnas.96.23.13191

Figure 4.

Figure 4

Comparison of the CGH profiles of chromosomes 4, 5, and 14 among PARP−/− mice (A) and immortalized PARP−/− (B) and PARP−/−(+PARP) (C) fibroblasts. Average ratio profiles were computed for all chromosomes from at least eight metaphase spreads as described in Fig. 3, with only the results for chromosomes 4, 5, and 14 shown. PARP−/−(+PARP) fibroblasts did not show the gains at 4C5-ter, 5F-ter, or 14A1-C2 that were apparent in both PARP−/− mice and immortalized PARP−/− cells, although they retained the partial loss at 14D3-ter.