Table 3.

Synthetic lethality studies with bir1Δ and various kinetochore mutants

Double-mutant genotype	Phenotype	Total no. of tetrads
bir1Δndc10-1	Viable	29
bir1Δcep3-1	Viable	29
bir1Δctf13-30	Viable	34
bir1Δcbf1Δ	SL	65
bir1Δctf19Δ	SL	16
bir1Δmcm21Δ	Viable	36
bir1Δokp1-5	Viable	29
bir1Δmif2-3	Viable	31
bir1Δcse4-1	Viable	33
bir1Δslk19Δ	Viable	39

SL, synthetic lethality. Heterozygous diploids containing bir1Δ and the various kinetochore protein mutations listed above were sporulated; tetrads were dissected; and the haploid progeny were scored for presence of the double mutations. SL indicates no viable double mutants found in the number of tetrads listed above.