Figure 5.

The SAM and the CRIC domains of CNK are required for the cooperation with RAS1. Scanning electron micrographs of adult eyes of the following genotypes: (A) UAS-RAS1^V12G37/+; sE-GAL4/+, (B) UAS-RAS1^V12G37/+; UAS-CNK^N-term/+; sE-GAL4/+, (C) UAS-RAS1^V12G37/+; UAS-CNK^N-termSAMmut/+; sE-GAL4/+, (D) UAS-RAS1^V12G37/+; UAS-CNK^{N-termCRICmut}/+; sE-GAL4/+, and (E) UAS-RAS1^V12G37/+; UAS-CNK^N-termPDZmut/+; sE-GAL4/+. At least three independent transformants for each CNK^N-term construct were tested. The phenotypes were uniform in all cases. Anterior is to the right.