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. 2008 Mar 10;105(11):4295–4300. doi: 10.1073/pnas.0711986105

Table 4.

Relation of AChEi-relevant exposures to illness in GWV

Outcome* Analysis Comparison type Exposure§ Result 95% C.I. Significance
No. general health symptoms Negative binomial regression Ratio of mean no. symptoms (with exposure/without) PB pills 1.4 1.2–1.5 P < 0.001
Pesticides 1.3 1.2–1.5 P < 0.001
Chemical weapons 1.3 1.2–1.5 P < 0.001
Functional impairment in the last 2 weeks Logistic regression Odds ratio PB 1.8 1.2–2.6 P = 0.004
Pesticides 1.5 1.1–2.0 P = 0.013
Chemical weapons 2.3 1.6–3.4 P < 001.0
SF-12 PCS Linear regression Difference in mean PB −2.5 −3.8, −1.2 P < 0.001
Pesticides −3.4 −4.6, −2.3 P < 0.001
Chemical weapons −3.7 −5.3, −2.1 P < 0.001
SF-12 MCS Linear regression Difference in mean PB −2.0 −3.6, −1.4 P = 0.012
Pesticides −3.4 −4.8, −2.1 P < 0.001
Chemical weapons −4.3 −6.2, −2.3 P < 0.001

See Australian GWV study (15).

*Measured outcomes are distinct from ″Gulf War illness″ definitions but may be expected to be elevated in the setting of Gulf War illness.

Adjustments: service type, rank, age (<20, 20–24, 25–34, >35 years), education, and marital status.

Compares exposed group vs nonexposed. Ratio of mean = exposed/unexposed. OR = exposed/unexposed. Difference = exposed − unexposed. For SF-12 PCS and MCS, lower scores are worse.

§Exposures defined as: PB pills (any vs none); pesticides/insecticides; and chemical weapons area.