Fig. 6.

Characterization of the AS021 locus. (a) The 2-Mb region containing an AmnSINE1 element in the AS021 locus in human chromosome 2. Coordinate (Top), AS021 locus (Middle), and gene annotations (Bottom) are based on the hg18 assembly in the UCSC genome browser (http://genome.ucsc.edu). (b) The 3.0-kb region around the AS021 locus and conservation among vertebrate species. The red horizontal bar indicates the putative full-length AmnSINE1 element. Within the bar, the red fill indicates an element that can be aligned with the AmnSINE1 consensus sequence. The display form is in accord with Fig. 3b. (c–j) lacZ expression patterns in an AS021 transgenic mouse embryos (E13.5). Lateral (c and g) and frontal (d and h) views of lacZ-stained whole-mount embryo are shown. The dashed line indicates where the embryo was sectioned for the staining shown in the coronal section (e and i). Arrowheads indicate lacZ expression in the neocortex. Arrows indicate the antihem (the border of the pallium and subpallium). [Scale bars: 2.0 mm (c, d, g, and h), 0.5 mm (e and i), and 0.2 mm (f and j).]