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. 2008 Mar 7;105(11):4453–4458. doi: 10.1073/pnas.0800897105

Fig. 5.

Fig. 5.

Core structure of the PSD based on tomographic reconstructions. Components and spacings between components are drawn approximately to scale. Dominant structure is an array of vertical filaments containing PSD-95 (red). NMDAR-type structures, differentiated by their large cytoplasmic extensions (cyan), concentrate in the center of the PSD. AMPAR-type structures, differentiated by their flattened cytoplasmic aspects (blue), surround the NMDAR structures. Virtually all NMDAR- and AMPAR-type structures are contacted by vertical filaments. Short horizontal filaments (purple) link vertical filaments associated with both NMDAR- and AMPAR-type structures. Longer horizontal filaments (white) concentrated under the NMDAR-type structures cross-link the vertical filament meshwork.