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PPARδ increases HDL-c in apoE−/− mice. (A) GW does not affect weight gain. (B–D) Similar levels of serum triglyceride, free fatty acid (FFA), and cholesterol are observed between vehicle- and GW-treated groups. C, chow diet; HF, high-fat diet; HF+GW, high-fat diet with GW treatment. (E) An increase in HDL cholesterol occurs in GW-treated apoE−/− mice. *, P < 0.05.
