Table 3.
Haplotype statistics using rs2180341, rs6569479, rs6569480, and rs7776136 in the RNF146; ECHDC1 locus
| Haplotype | Genotype | Phase 1 |
Phase 2 |
Aggregate study |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| P | n | OR (CI) | P | n | OR (CI) | P | n | OR (CI) | ||
| H1 | ACGT | 5.53 × 10−5 | 829 | 0.56 (0.42–0.75) | 1.30 × 10−4 | 2,889 | 0.75 (0.65–0.87) | 2.05 × 10−9 | 4,367 | 0.69 (0.61–0.78) |
| H2 | GTAA | 2.79 × 10−2 | 241 | 1.39 (1.03–1.87) | 1.11 × 10−4 | 939 | 1.34 (1.15–1.55) | 1.33 × 10−7 | 1,382 | 1.39 (1.23–1.57) |
In the phase 1 and aggregate studies, ≈4% of the subjects were imputed to possess five rare haplotypes not shown here. NS, not significant.