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. 1995 Dec;59(4):548–578. doi: 10.1128/mr.59.4.548-578.1995

Genetic elements of plant viruses as tools for genetic engineering.

A R Mushegian 1, R J Shepherd 1
PMCID: PMC239387  PMID: 8531885

Abstract

Viruses have developed successful strategies for propagation at the expense of their host cells. Efficient gene expression, genome multiplication, and invasion of the host are enabled by virus-encoded genetic elements, many of which are well characterized. Sequences derived from plant DNA and RNA viruses can be used to control expression of other genes in vivo. The main groups of plant virus genetic elements useful in genetic engineering are reviewed, including the signals for DNA-dependent and RNA-dependent RNA synthesis, sequences on the virus mRNAs that enable translational control, and sequences that control processing and intracellular sorting of virus proteins. Use of plant viruses as extrachromosomal expression vectors is also discussed, along with the issue of their stability.

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Selected References

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  1. Abel S., Theologis A. Transient transformation of Arabidopsis leaf protoplasts: a versatile experimental system to study gene expression. Plant J. 1994 Mar;5(3):421–427. doi: 10.1111/j.1365-313x.1994.00421.x. [DOI] [PubMed] [Google Scholar]
  2. Accotto G. P., Donson J., Mullineaux P. M. Mapping of Digitaria streak virus transcripts reveals different RNA species from the same transcription unit. EMBO J. 1989 Apr;8(4):1033–1039. doi: 10.1002/j.1460-2075.1989.tb03470.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Agol V. I. The 5'-untranslated region of picornaviral genomes. Adv Virus Res. 1991;40:103–180. doi: 10.1016/S0065-3527(08)60278-X. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Agranovsky A. A., Koonin E. V., Boyko V. P., Maiss E., Frötschl R., Lunina N. A., Atabekov J. G. Beet yellows closterovirus: complete genome structure and identification of a leader papain-like thiol protease. Virology. 1994 Jan;198(1):311–324. doi: 10.1006/viro.1994.1034. [DOI] [PubMed] [Google Scholar]
  5. Ahlquist P., French R., Bujarski J. J. Molecular studies of brome mosaic virus using infectious transcripts from cloned cDNA. Adv Virus Res. 1987;32:215–242. doi: 10.1016/s0065-3527(08)60478-9. [DOI] [PubMed] [Google Scholar]
  6. Allison R., Thompson C., Ahlquist P. Regeneration of a functional RNA virus genome by recombination between deletion mutants and requirement for cowpea chlorotic mottle virus 3a and coat genes for systemic infection. Proc Natl Acad Sci U S A. 1990 Mar;87(5):1820–1824. doi: 10.1073/pnas.87.5.1820. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Aran J. M., Gottesman M. M., Pastan I. Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector. Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3176–3180. doi: 10.1073/pnas.91.8.3176. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Assaad F. F., Signer E. R. Cauliflower mosaic virus P35S promoter activity in Escherichia coli. Mol Gen Genet. 1990 Sep;223(3):517–520. doi: 10.1007/BF00264462. [DOI] [PubMed] [Google Scholar]
  9. Atkins J. F., Weiss R. B., Gesteland R. F. Ribosome gymnastics--degree of difficulty 9.5, style 10.0. Cell. 1990 Aug 10;62(3):413–423. doi: 10.1016/0092-8674(90)90007-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Baer M. L., Houser F., Loesch-Fries L. S., Gehrke L. Specific RNA binding by amino-terminal peptides of alfalfa mosaic virus coat protein. EMBO J. 1994 Feb 1;13(3):727–735. doi: 10.1002/j.1460-2075.1994.tb06312.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Basso J., Dallaire P., Charest P. J., Devantier Y., Laliberté J. F. Evidence for an internal ribosome entry site within the 5' non-translated region of turnip mosaic potyvirus RNA. J Gen Virol. 1994 Nov;75(Pt 11):3157–3165. doi: 10.1099/0022-1317-75-11-3157. [DOI] [PubMed] [Google Scholar]
  12. Battraw M. J., Hall T. C. Histochemical analysis of CaMV 35S promoter-beta-glucuronidase gene expression in transgenic rice plants. Plant Mol Biol. 1990 Oct;15(4):527–538. doi: 10.1007/BF00017828. [DOI] [PubMed] [Google Scholar]
  13. Baughman G. A., Jacobs J. D., Howell S. H. Cauliflower mosaic virus gene VI produces a symptomatic phenotype in transgenic tobacco plants. Proc Natl Acad Sci U S A. 1988 Feb;85(3):733–737. doi: 10.1073/pnas.85.3.733. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Beck D. L., Guilford P. J., Voot D. M., Andersen M. T., Forster R. L. Triple gene block proteins of white clover mosaic potexvirus are required for transport. Virology. 1991 Aug;183(2):695–702. doi: 10.1016/0042-6822(91)90998-q. [DOI] [PubMed] [Google Scholar]
  15. Beier H., Barciszewska M., Krupp G., Mitnacht R., Gross H. J. UAG readthrough during TMV RNA translation: isolation and sequence of two tRNAs with suppressor activity from tobacco plants. EMBO J. 1984 Feb;3(2):351–356. doi: 10.1002/j.1460-2075.1984.tb01810.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Beljanski M. L'ARN isolé du virus de la mosaique jaune du navet; accepteur des L-acides aminés en présence d'enzymes bactériens. Bull Soc Chim Biol (Paris) 1965;47(8):1645–1652. [PubMed] [Google Scholar]
  17. Belsham G. J., Lomonossoff G. P. The mechanism of translation of cowpea mosaic virus middle component RNA: no evidence for internal initiation from experiments in an animal cell transient expression system. J Gen Virol. 1991 Dec;72(Pt 12):3109–3113. doi: 10.1099/0022-1317-72-12-3109. [DOI] [PubMed] [Google Scholar]
  18. Benfey P. N., Chua N. H. The Cauliflower Mosaic Virus 35S Promoter: Combinatorial Regulation of Transcription in Plants. Science. 1990 Nov 16;250(4983):959–966. doi: 10.1126/science.250.4983.959. [DOI] [PubMed] [Google Scholar]
  19. Benfey P. N., Ren L., Chua N. H. Combinatorial and synergistic properties of CaMV 35S enhancer subdomains. EMBO J. 1990 Jun;9(6):1685–1696. doi: 10.1002/j.1460-2075.1990.tb08292.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Benfey P. N., Ren L., Chua N. H. The CaMV 35S enhancer contains at least two domains which can confer different developmental and tissue-specific expression patterns. EMBO J. 1989 Aug;8(8):2195–2202. doi: 10.1002/j.1460-2075.1989.tb08342.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Benfey P. N., Ren L., Chua N. H. Tissue-specific expression from CaMV 35S enhancer subdomains in early stages of plant development. EMBO J. 1990 Jun;9(6):1677–1684. doi: 10.1002/j.1460-2075.1990.tb08291.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Berna A., Gafny R., Wolf S., Lucas W. J., Holt C. A., Beachy R. N. The TMV movement protein: role of the C-terminal 73 amino acids in subcellular localization and function. Virology. 1991 Jun;182(2):682–689. doi: 10.1016/0042-6822(91)90609-f. [DOI] [PubMed] [Google Scholar]
  23. Bhattacharyya-Pakrasi M., Peng J., Elmer J. S., Laco G., Shen P., Kaniewska M. B., Kononowicz H., Wen F., Hodges T. K., Beachy R. N. Specificity of a promoter from the rice tungro bacilliform virus for expression in phloem tissues. Plant J. 1993 Jul;4(1):71–79. doi: 10.1046/j.1365-313x.1993.04010071.x. [DOI] [PubMed] [Google Scholar]
  24. Bienroth S., Keller W., Wahle E. Assembly of a processive messenger RNA polyadenylation complex. EMBO J. 1993 Feb;12(2):585–594. doi: 10.1002/j.1460-2075.1993.tb05690.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Boccard F., Baulcombe D. Mutational analysis of cis-acting sequences and gene function in RNA3 of cucumber mosaic virus. Virology. 1993 Apr;193(2):563–578. doi: 10.1006/viro.1993.1165. [DOI] [PubMed] [Google Scholar]
  26. Bonneville J. M., Sanfaçon H., Fütterer J., Hohn T. Posttranscriptional trans-activation in cauliflower mosaic virus. Cell. 1989 Dec 22;59(6):1135–1143. doi: 10.1016/0092-8674(89)90769-1. [DOI] [PubMed] [Google Scholar]
  27. Boulton M. I., Pallaghy C. K., Chatani M., MacFarlane S., Davies J. W. Replication of maize streak virus mutants in maize protoplasts: evidence for a movement protein. Virology. 1993 Jan;192(1):85–93. doi: 10.1006/viro.1993.1010. [DOI] [PubMed] [Google Scholar]
  28. Boulton M. I., Steinkellner H., Donson J., Markham P. G., King D. I., Davies J. W. Mutational analysis of the virion-sense genes of maize streak virus. J Gen Virol. 1989 Sep;70(Pt 9):2309–2323. doi: 10.1099/0022-1317-70-9-2309. [DOI] [PubMed] [Google Scholar]
  29. Boyer J. C., Haenni A. L. Infectious transcripts and cDNA clones of RNA viruses. Virology. 1994 Feb;198(2):415–426. doi: 10.1006/viro.1994.1053. [DOI] [PubMed] [Google Scholar]
  30. Bozarth C. S., Weiland J. J., Dreher T. W. Expression of ORF-69 of turnip yellow mosaic virus is necessary for viral spread in plants. Virology. 1992 Mar;187(1):124–130. doi: 10.1016/0042-6822(92)90301-5. [DOI] [PubMed] [Google Scholar]
  31. Brierley I., Rolley N. J., Jenner A. J., Inglis S. C. Mutational analysis of the RNA pseudoknot component of a coronavirus ribosomal frameshifting signal. J Mol Biol. 1991 Aug 20;220(4):889–902. doi: 10.1016/0022-2836(91)90361-9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Bujarski J. J., Kaesberg P. Genetic recombination between RNA components of a multipartite plant virus. 1986 May 29-Jun 4Nature. 321(6069):528–531. doi: 10.1038/321528a0. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Burgyan J., Rubino L., Russo M. De novo generation of cymbidium ringspot virus defective interfering RNA. J Gen Virol. 1991 Mar;72(Pt 3):505–509. doi: 10.1099/0022-1317-72-3-505. [DOI] [PubMed] [Google Scholar]
  34. Burgyán J., Salánki K., Dalmay T., Russo M. Expression of homologous and heterologous viral coat protein-encoding genes using recombinant DI RNA from cymbidium ringspot tombusvirus. Gene. 1994 Jan 28;138(1-2):159–163. doi: 10.1016/0378-1119(94)90800-1. [DOI] [PubMed] [Google Scholar]
  35. Burns D. P., Desrosiers R. C. Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys. J Virol. 1991 Apr;65(4):1843–1854. doi: 10.1128/jvi.65.4.1843-1854.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Carrington J. C., Cary S. M., Parks T. D., Dougherty W. G. A second proteinase encoded by a plant potyvirus genome. EMBO J. 1989 Feb;8(2):365–370. doi: 10.1002/j.1460-2075.1989.tb03386.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Carrington J. C., Dougherty W. G. Small nuclear inclusion protein encoded by a plant potyvirus genome is a protease. J Virol. 1987 Aug;61(8):2540–2548. doi: 10.1128/jvi.61.8.2540-2548.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Carrington J. C., Freed D. D., Leinicke A. J. Bipartite signal sequence mediates nuclear translocation of the plant potyviral NIa protein. Plant Cell. 1991 Sep;3(9):953–962. doi: 10.1105/tpc.3.9.953. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Carrington J. C., Haldeman R., Dolja V. V., Restrepo-Hartwig M. A. Internal cleavage and trans-proteolytic activities of the VPg-proteinase (NIa) of tobacco etch potyvirus in vivo. J Virol. 1993 Dec;67(12):6995–7000. doi: 10.1128/jvi.67.12.6995-7000.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Cascone P. J., Haydar T. F., Simon A. E. Sequences and structures required for recombination between virus-associated RNAs. Science. 1993 May 7;260(5109):801–805. doi: 10.1126/science.8484119. [DOI] [PubMed] [Google Scholar]
  41. Caspar D. L., Namba K. Switching in the self-assembly of tobacco mosaic virus. Adv Biophys. 1990;26:157–185. doi: 10.1016/0065-227x(90)90011-h. [DOI] [PubMed] [Google Scholar]
  42. Castanotto D., Rossi J. J., Deshler J. O. Biological and functional aspects of catalytic RNAs. Crit Rev Eukaryot Gene Expr. 1992;2(4):331–357. [PubMed] [Google Scholar]
  43. Cavener D. R., Ray S. C. Eukaryotic start and stop translation sites. Nucleic Acids Res. 1991 Jun 25;19(12):3185–3192. doi: 10.1093/nar/19.12.3185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Chapman S., Kavanagh T., Baulcombe D. Potato virus X as a vector for gene expression in plants. Plant J. 1992 Jul;2(4):549–557. doi: 10.1046/j.1365-313x.1992.t01-24-00999.x. [DOI] [PubMed] [Google Scholar]
  45. Chen G., Müller M., Potrykus I., Hohn T., Fütterer J. Rice tungro bacilliform virus: transcription and translation in protoplasts. Virology. 1994 Oct;204(1):91–100. doi: 10.1006/viro.1994.1513. [DOI] [PubMed] [Google Scholar]
  46. Chen Z. L., Pan N. S., Beachy R. N. A DNA sequence element that confers seed-specific enhancement to a constitutive promoter. EMBO J. 1988 Feb;7(2):297–302. doi: 10.1002/j.1460-2075.1988.tb02812.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Citovsky V., Knorr D., Zambryski P. Gene I, a potential cell-to-cell movement locus of cauliflower mosaic virus, encodes an RNA-binding protein. Proc Natl Acad Sci U S A. 1991 Mar 15;88(6):2476–2480. doi: 10.1073/pnas.88.6.2476. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Culver J. N., Lehto K., Close S. M., Hilf M. E., Dawson W. O. Genomic position affects the expression of tobacco mosaic virus movement and coat protein genes. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):2055–2059. doi: 10.1073/pnas.90.5.2055. [DOI] [PMC free article] [PubMed] [Google Scholar]
  49. Culver J. N., Stubbs G., Dawson W. O. Structure-function relationship between tobacco mosaic virus coat protein and hypersensitivity in Nicotiana sylvestris. J Mol Biol. 1994 Sep 16;242(2):130–138. doi: 10.1006/jmbi.1994.1564. [DOI] [PubMed] [Google Scholar]
  50. Dalmay T., Rubino L., Burgyán J., Kollár A., Russo M. Functional analysis of cymbidium ringspot virus genome. Virology. 1993 Jun;194(2):697–704. doi: 10.1006/viro.1993.1310. [DOI] [PubMed] [Google Scholar]
  51. Danthinne X., Seurinck J., Meulewaeter F., Van Montagu M., Cornelissen M. The 3' untranslated region of satellite tobacco necrosis virus RNA stimulates translation in vitro. Mol Cell Biol. 1993 Jun;13(6):3340–3349. doi: 10.1128/mcb.13.6.3340. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Dawson W. O., Lewandowski D. J., Hilf M. E., Bubrick P., Raffo A. J., Shaw J. J., Grantham G. L., Desjardins P. R. A tobacco mosaic virus-hybrid expresses and loses an added gene. Virology. 1989 Sep;172(1):285–292. doi: 10.1016/0042-6822(89)90130-x. [DOI] [PubMed] [Google Scholar]
  53. Dawson W. O. Tobamovirus-plant interactions. Virology. 1992 Feb;186(2):359–367. doi: 10.1016/0042-6822(92)90001-6. [DOI] [PubMed] [Google Scholar]
  54. De Tapia M., Himmelbach A., Hohn T. Molecular dissection of the cauliflower mosaic virus translation transactivator. EMBO J. 1993 Aug;12(8):3305–3314. doi: 10.1002/j.1460-2075.1993.tb06000.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. De Zoeten G. A., Penswick J. R., Horisberger M. A., Ahl P., Schultze M., Hohn T. The expression, localization, and effect of a human interferon in plants. Virology. 1989 Sep;172(1):213–222. doi: 10.1016/0042-6822(89)90123-2. [DOI] [PubMed] [Google Scholar]
  56. Demler S. A., Rucker D. G., de Zoeten G. A. The chimeric nature of the genome of pea enation mosaic virus: the independent replication of RNA 2. J Gen Virol. 1993 Jan;74(Pt 1):1–14. doi: 10.1099/0022-1317-74-1-1. [DOI] [PubMed] [Google Scholar]
  57. Deom C. M., Lapidot M., Beachy R. N. Plant virus movement proteins. Cell. 1992 Apr 17;69(2):221–224. doi: 10.1016/0092-8674(92)90403-y. [DOI] [PubMed] [Google Scholar]
  58. Di R., Dinesh-Kumar S. P., Miller W. A. Translational frameshifting by barley yellow dwarf virus RNA (PAV serotype) in Escherichia coli and in eukaryotic cell-free extracts. Mol Plant Microbe Interact. 1993 Jul-Aug;6(4):444–452. doi: 10.1094/mpmi-6-444. [DOI] [PubMed] [Google Scholar]
  59. Dinesh-Kumar S. P., Brault V., Miller W. A. Precise mapping and in vitro translation of a trifunctional subgenomic RNA of barley yellow dwarf virus. Virology. 1992 Apr;187(2):711–722. doi: 10.1016/0042-6822(92)90474-4. [DOI] [PubMed] [Google Scholar]
  60. Ding B., Li Q., Nguyen L., Palukaitis P., Lucas W. J. Cucumber mosaic virus 3a protein potentiates cell-to-cell trafficking of CMV RNA in tobacco plants. Virology. 1995 Mar 10;207(2):345–353. doi: 10.1006/viro.1995.1093. [DOI] [PubMed] [Google Scholar]
  61. Dingwall C., Laskey R. A. Nuclear targeting sequences--a consensus? Trends Biochem Sci. 1991 Dec;16(12):478–481. doi: 10.1016/0968-0004(91)90184-w. [DOI] [PubMed] [Google Scholar]
  62. Dingwall C., Laskey R. A. Nucleoplasmin: the archetypal molecular chaperone. Semin Cell Biol. 1990 Feb;1(1):11–17. [PubMed] [Google Scholar]
  63. Dingwall C., Laskey R. The nuclear membrane. Science. 1992 Nov 6;258(5084):942–947. doi: 10.1126/science.1439805. [DOI] [PubMed] [Google Scholar]
  64. Dinman J. D., Wickner R. B. Ribosomal frameshifting efficiency and gag/gag-pol ratio are critical for yeast M1 double-stranded RNA virus propagation. J Virol. 1992 Jun;66(6):3669–3676. doi: 10.1128/jvi.66.6.3669-3676.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  65. Dolja V. V., Haldeman R., Robertson N. L., Dougherty W. G., Carrington J. C. Distinct functions of capsid protein in assembly and movement of tobacco etch potyvirus in plants. EMBO J. 1994 Mar 15;13(6):1482–1491. doi: 10.1002/j.1460-2075.1994.tb06403.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. Dolja V. V., Herndon K. L., Pirone T. P., Carrington J. C. Spontaneous mutagenesis of a plant potyvirus genome after insertion of a foreign gene. J Virol. 1993 Oct;67(10):5968–5975. doi: 10.1128/jvi.67.10.5968-5975.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Dolja V. V., McBride H. J., Carrington J. C. Tagging of plant potyvirus replication and movement by insertion of beta-glucuronidase into the viral polyprotein. Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10208–10212. doi: 10.1073/pnas.89.21.10208. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. Donson J., Kearney C. M., Hilf M. E., Dawson W. O. Systemic expression of a bacterial gene by a tobacco mosaic virus-based vector. Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7204–7208. doi: 10.1073/pnas.88.16.7204. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Donson J., Morris-Krsinich B. A., Mullineaux P. M., Boulton M. I., Davies J. W. A putative primer for second-strand DNA synthesis of maize streak virus is virion-associated. EMBO J. 1984 Dec 20;3(13):3069–3073. doi: 10.1002/j.1460-2075.1984.tb02260.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. Dougherty J. P., Temin H. M. Determination of the rate of base-pair substitution and insertion mutations in retrovirus replication. J Virol. 1988 Aug;62(8):2817–2822. doi: 10.1128/jvi.62.8.2817-2822.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  71. Dougherty W. G., Carrington J. C., Cary S. M., Parks T. D. Biochemical and mutational analysis of a plant virus polyprotein cleavage site. EMBO J. 1988 May;7(5):1281–1287. doi: 10.1002/j.1460-2075.1988.tb02942.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  72. Dougherty W. G., Semler B. L. Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes. Microbiol Rev. 1993 Dec;57(4):781–822. doi: 10.1128/mr.57.4.781-822.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Drake J. W. Rates of spontaneous mutation among RNA viruses. Proc Natl Acad Sci U S A. 1993 May 1;90(9):4171–4175. doi: 10.1073/pnas.90.9.4171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  74. Drake J. W. Spontaneous mutation. Annu Rev Genet. 1991;25:125–146. doi: 10.1146/annurev.ge.25.120191.001013. [DOI] [PubMed] [Google Scholar]
  75. Dreher T. W., Tsai C. H., Florentz C., Giegé R. Specific valylation of turnip yellow mosaic virus RNA by wheat germ valyl-tRNA synthetase determined by three anticodon loop nucleotides. Biochemistry. 1992 Sep 29;31(38):9183–9189. doi: 10.1021/bi00153a010. [DOI] [PubMed] [Google Scholar]
  76. Driesen M., Benito-Moreno R. M., Hohn T., Fütterer J. Transcription from the CaMV 19 S promoter and autocatalysis of translation from CaMV RNA. Virology. 1993 Jul;195(1):203–210. doi: 10.1006/viro.1993.1361. [DOI] [PubMed] [Google Scholar]
  77. Eagle P. A., Orozco B. M., Hanley-Bowdoin L. A DNA sequence required for geminivirus replication also mediates transcriptional regulation. Plant Cell. 1994 Aug;6(8):1157–1170. doi: 10.1105/tpc.6.8.1157. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Elmer J. S., Brand L., Sunter G., Gardiner W. E., Bisaro D. M., Rogers S. G. Genetic analysis of the tomato golden mosaic virus. II. The product of the AL1 coding sequence is required for replication. Nucleic Acids Res. 1988 Jul 25;16(14B):7043–7060. doi: 10.1093/nar/16.14.7043. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. Elmer S., Rogers S. G. Selection for wild type size derivatives of tomato golden mosaic virus during systemic infection. Nucleic Acids Res. 1990 Apr 25;18(8):2001–2006. doi: 10.1093/nar/18.8.2001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  80. Erny C., Schoumacher F., Jung C., Gagey M. J., Godefroy-Colburn T., Stussi-Garaud C., Berna A. An N-proximal sequence of the alfalfa mosaic virus movement protein is necessary for association with cell walls in transgenic plants. J Gen Virol. 1992 Aug;73(Pt 8):2115–2119. doi: 10.1099/0022-1317-73-8-2115. [DOI] [PubMed] [Google Scholar]
  81. Fang R. X., Nagy F., Sivasubramaniam S., Chua N. H. Multiple cis regulatory elements for maximal expression of the cauliflower mosaic virus 35S promoter in transgenic plants. Plant Cell. 1989 Jan;1(1):141–150. doi: 10.1105/tpc.1.1.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  82. Farabaugh P. J., Zhao H., Vimaladithan A. A novel programed frameshift expresses the POL3 gene of retrotransposon Ty3 of yeast: frameshifting without tRNA slippage. Cell. 1993 Jul 16;74(1):93–103. doi: 10.1016/0092-8674(93)90297-4. [DOI] [PMC free article] [PubMed] [Google Scholar]
  83. Felden B., Florentz C., Westhof E., Giegé R. Non-canonical substrates of aminoacyl-tRNA synthetases: the tRNA-like structure of brome mosaic virus genomic RNA. Biochimie. 1993;75(12):1143–1157. doi: 10.1016/0300-9084(93)90014-j. [DOI] [PubMed] [Google Scholar]
  84. Fenoll C., Black D. M., Howell S. H. The intergenic region of maize streak virus contains promoter elements involved in rightward transcription of the viral genome. EMBO J. 1988 Jun;7(6):1589–1596. doi: 10.1002/j.1460-2075.1988.tb02984.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  85. Fenoll C., Schwarz J. J., Black D. M., Schneider M., Howell S. H. The intergenic region of maize streak virus contains a GC-rich element that activates rightward transcription and binds maize nuclear factors. Plant Mol Biol. 1990 Dec;15(6):865–877. doi: 10.1007/BF00039426. [DOI] [PubMed] [Google Scholar]
  86. Flavell R. B. Inactivation of gene expression in plants as a consequence of specific sequence duplication. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3490–3496. doi: 10.1073/pnas.91.9.3490. [DOI] [PMC free article] [PubMed] [Google Scholar]
  87. Fraenkel-Conrat H., Williams R. C. RECONSTITUTION OF ACTIVE TOBACCO MOSAIC VIRUS FROM ITS INACTIVE PROTEIN AND NUCLEIC ACID COMPONENTS. Proc Natl Acad Sci U S A. 1955 Oct 15;41(10):690–698. doi: 10.1073/pnas.41.10.690. [DOI] [PMC free article] [PubMed] [Google Scholar]
  88. French R., Ahlquist P. Characterization and engineering of sequences controlling in vivo synthesis of brome mosaic virus subgenomic RNA. J Virol. 1988 Jul;62(7):2411–2420. doi: 10.1128/jvi.62.7.2411-2420.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  89. French R., Ahlquist P. Intercistronic as well as terminal sequences are required for efficient amplification of brome mosaic virus RNA3. J Virol. 1987 May;61(5):1457–1465. doi: 10.1128/jvi.61.5.1457-1465.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  90. French R., Janda M., Ahlquist P. Bacterial gene inserted in an engineered RNA virus: efficient expression in monocotyledonous plant cells. Science. 1986 Mar 14;231(4743):1294–1297. doi: 10.1126/science.231.4743.1294. [DOI] [PubMed] [Google Scholar]
  91. Frolov I., Schlesinger S. Translation of Sindbis virus mRNA: effects of sequences downstream of the initiating codon. J Virol. 1994 Dec;68(12):8111–8117. doi: 10.1128/jvi.68.12.8111-8117.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  92. Fujiwara T., Giesman-Cookmeyer D., Ding B., Lommel S. A., Lucas W. J. Cell-to-Cell Trafficking of Macromolecules through Plasmodesmata Potentiated by the Red Clover Necrotic Mosaic Virus Movement Protein. Plant Cell. 1993 Dec;5(12):1783–1794. doi: 10.1105/tpc.5.12.1783. [DOI] [PMC free article] [PubMed] [Google Scholar]
  93. Fütterer J., Hohn T. Translation of a polycistronic mRNA in the presence of the cauliflower mosaic virus transactivator protein. EMBO J. 1991 Dec;10(12):3887–3896. doi: 10.1002/j.1460-2075.1991.tb04958.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  94. Gafny R., Lapidot M., Berna A., Holt C. A., Deom C. M., Beachy R. N. Effects of terminal deletion mutations on function of the movement protein of tobacco mosaic virus. Virology. 1992 Apr;187(2):499–507. doi: 10.1016/0042-6822(92)90452-u. [DOI] [PubMed] [Google Scholar]
  95. Gal S., Pisan B., Hohn T., Grimsley N., Hohn B. Genomic homologous recombination in planta. EMBO J. 1991 Jun;10(6):1571–1578. doi: 10.1002/j.1460-2075.1991.tb07677.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  96. Gallie D. R., Feder J. N., Schimke R. T., Walbot V. Functional analysis of the tobacco mosaic virus tRNA-like structure in cytoplasmic gene regulation. Nucleic Acids Res. 1991 Sep 25;19(18):5031–5036. doi: 10.1093/nar/19.18.5031. [DOI] [PMC free article] [PubMed] [Google Scholar]
  97. Gallie D. R., Kado C. I. A translational enhancer derived from tobacco mosaic virus is functionally equivalent to a Shine-Dalgarno sequence. Proc Natl Acad Sci U S A. 1989 Jan;86(1):129–132. doi: 10.1073/pnas.86.1.129. [DOI] [PMC free article] [PubMed] [Google Scholar]
  98. Gallie D. R., Lucas W. J., Walbot V. Visualizing mRNA expression in plant protoplasts: factors influencing efficient mRNA uptake and translation. Plant Cell. 1989 Mar;1(3):301–311. doi: 10.1105/tpc.1.3.301. [DOI] [PMC free article] [PubMed] [Google Scholar]
  99. Gallie D. R., Sleat D. E., Watts J. W., Turner P. C., Wilson T. M. The 5'-leader sequence of tobacco mosaic virus RNA enhances the expression of foreign gene transcripts in vitro and in vivo. Nucleic Acids Res. 1987 Apr 24;15(8):3257–3273. doi: 10.1093/nar/15.8.3257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  100. Gallie D. R. The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency. Genes Dev. 1991 Nov;5(11):2108–2116. doi: 10.1101/gad.5.11.2108. [DOI] [PubMed] [Google Scholar]
  101. Gallie D. R., Walbot V. Identification of the motifs within the tobacco mosaic virus 5'-leader responsible for enhancing translation. Nucleic Acids Res. 1992 Sep 11;20(17):4631–4638. doi: 10.1093/nar/20.17.4631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  102. Gallie D. R., Walbot V. RNA pseudoknot domain of tobacco mosaic virus can functionally substitute for a poly(A) tail in plant and animal cells. Genes Dev. 1990 Jul;4(7):1149–1157. doi: 10.1101/gad.4.7.1149. [DOI] [PubMed] [Google Scholar]
  103. Gatz C., Frohberg C., Wendenburg R. Stringent repression and homogeneous de-repression by tetracycline of a modified CaMV 35S promoter in intact transgenic tobacco plants. Plant J. 1992 May;2(3):397–404. doi: 10.1111/j.1365-313x.1992.00397.x. [DOI] [PubMed] [Google Scholar]
  104. Gesteland R. F., Weiss R. B., Atkins J. F. Recoding: reprogrammed genetic decoding. Science. 1992 Sep 18;257(5077):1640–1641. doi: 10.1126/science.1529352. [DOI] [PubMed] [Google Scholar]
  105. Giegé R., Florentz C., Dreher T. W. The TYMV tRNA-like structure. Biochimie. 1993;75(7):569–582. doi: 10.1016/0300-9084(93)90063-X. [DOI] [PMC free article] [PubMed] [Google Scholar]
  106. Gilmer D., Richards K., Jonard G., Guilley H. cis-active sequences near the 5'-termini of beet necrotic yellow vein virus RNAs 3 and 4. Virology. 1992 Sep;190(1):55–67. doi: 10.1016/0042-6822(92)91192-w. [DOI] [PubMed] [Google Scholar]
  107. Gmünder H., Kohli J. Cauliflower mosaic virus promoters direct efficient expression of a bacterial G418 resistance gene in Schizosaccharomyces pombe. Mol Gen Genet. 1989 Dec;220(1):95–101. doi: 10.1007/BF00260862. [DOI] [PubMed] [Google Scholar]
  108. Goelet P., Lomonossoff G. P., Butler P. J., Akam M. E., Gait M. J., Karn J. Nucleotide sequence of tobacco mosaic virus RNA. Proc Natl Acad Sci U S A. 1982 Oct;79(19):5818–5822. doi: 10.1073/pnas.79.19.5818. [DOI] [PMC free article] [PubMed] [Google Scholar]
  109. Goldbach R. Genome similarities between plant and animal RNA viruses. Microbiol Sci. 1987 Jul;4(7):197–202. [PubMed] [Google Scholar]
  110. Goodman M. F., Creighton S., Bloom L. B., Petruska J. Biochemical basis of DNA replication fidelity. Crit Rev Biochem Mol Biol. 1993;28(2):83–126. doi: 10.3109/10409239309086792. [DOI] [PubMed] [Google Scholar]
  111. Gorbalenya A. E., Koonin E. V., Donchenko A. P., Blinov V. M. A novel superfamily of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination. FEBS Lett. 1988 Aug 1;235(1-2):16–24. doi: 10.1016/0014-5793(88)81226-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  112. Gorbalenya A. E., Koonin E. V. Viral proteins containing the purine NTP-binding sequence pattern. Nucleic Acids Res. 1989 Nov 11;17(21):8413–8440. doi: 10.1093/nar/17.21.8413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  113. Gorbalenya A. E., Koonin E. V., Wolf Y. I. A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses. FEBS Lett. 1990 Mar 12;262(1):145–148. doi: 10.1016/0014-5793(90)80175-i. [DOI] [PubMed] [Google Scholar]
  114. Gowda S., Scholthof H. B., Wu F. C., Shepherd R. J. Requirement of gene VII in cis for the expression of downstream genes on the major transcript of figwort mosaic virus. Virology. 1991 Dec;185(2):867–871. doi: 10.1016/0042-6822(91)90561-o. [DOI] [PubMed] [Google Scholar]
  115. Gowda S., Wu F. C., Scholthof H. B., Shepherd R. J. Gene VI of figwort mosaic virus (caulimovirus group) functions in posttranscriptional expression of genes on the full-length RNA transcript. Proc Natl Acad Sci U S A. 1989 Dec;86(23):9203–9207. doi: 10.1073/pnas.86.23.9203. [DOI] [PMC free article] [PubMed] [Google Scholar]
  116. Green P. J. Control of mRNA Stability in Higher Plants. Plant Physiol. 1993 Aug;102(4):1065–1070. doi: 10.1104/pp.102.4.1065. [DOI] [PMC free article] [PubMed] [Google Scholar]
  117. Greene A. E., Allison R. F. Recombination between viral RNA and transgenic plant transcripts. Science. 1994 Mar 11;263(5152):1423–1425. doi: 10.1126/science.8128222. [DOI] [PubMed] [Google Scholar]
  118. Guerineau F., Brooks L., Mullineaux P. Effect of deletions in the cauliflower mosaic virus polyadenylation sequence on the choice of the polyadenylation sites in tobacco protoplasts. Mol Gen Genet. 1991 Apr;226(1-2):141–144. doi: 10.1007/BF00273597. [DOI] [PubMed] [Google Scholar]
  119. Guerrier-Takada C., van Belkum A., Pleij C. W., Altman S. Novel reactions of RNAase P with a tRNA-like structure in turnip yellow mosaic virus RNA. Cell. 1988 Apr 22;53(2):267–272. doi: 10.1016/0092-8674(88)90388-1. [DOI] [PubMed] [Google Scholar]
  120. Haley A., Zhan X., Richardson K., Head K., Morris B. Regulation of the activities of African cassava mosaic virus promoters by the AC1, AC2, and AC3 gene products. Virology. 1992 Jun;188(2):905–909. doi: 10.1016/0042-6822(92)90551-y. [DOI] [PubMed] [Google Scholar]
  121. Hamamoto H., Sugiyama Y., Nakagawa N., Hashida E., Matsunaga Y., Takemoto S., Watanabe Y., Okada Y. A new tobacco mosaic virus vector and its use for the systemic production of angiotensin-I-converting enzyme inhibitor in transgenic tobacco and tomato. Biotechnology (N Y) 1993 Aug;11(8):930–932. doi: 10.1038/nbt0893-930. [DOI] [PubMed] [Google Scholar]
  122. Hanley-Bowdoin L., Elmer J. S., Rogers S. G. Expression of functional replication protein from tomato golden mosaic virus in transgenic tobacco plants. Proc Natl Acad Sci U S A. 1990 Feb;87(4):1446–1450. doi: 10.1073/pnas.87.4.1446. [DOI] [PMC free article] [PubMed] [Google Scholar]
  123. Hasegawa A., Verver J., Shimada A., Saito M., Goldbach R., Van Kammen A., Miki K., Kameya-Iwaki M., Hibi T. The complete sequence of soybean chlorotic mottle virus DNA and the identification of a novel promoter. Nucleic Acids Res. 1989 Dec 11;17(23):9993–10013. doi: 10.1093/nar/17.23.9993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  124. Haseloff J., Goelet P., Zimmern D., Ahlquist P., Dasgupta R., Kaesberg P. Striking similarities in amino acid sequence among nonstructural proteins encoded by RNA viruses that have dissimilar genomic organization. Proc Natl Acad Sci U S A. 1984 Jul;81(14):4358–4362. doi: 10.1073/pnas.81.14.4358. [DOI] [PMC free article] [PubMed] [Google Scholar]
  125. Hatfield D. L., Levin J. G., Rein A., Oroszlan S. Translational suppression in retroviral gene expression. Adv Virus Res. 1992;41:193–239. doi: 10.1016/S0065-3527(08)60037-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  126. Hayes R. J., Buck K. W. Complete replication of a eukaryotic virus RNA in vitro by a purified RNA-dependent RNA polymerase. Cell. 1990 Oct 19;63(2):363–368. doi: 10.1016/0092-8674(90)90169-f. [DOI] [PubMed] [Google Scholar]
  127. Hayes R. J., Coutts R. H., Buck K. W. Stability and expression of bacterial genes in replicating geminivirus vectors in plants. Nucleic Acids Res. 1989 Apr 11;17(7):2391–2403. doi: 10.1093/nar/17.7.2391. [DOI] [PMC free article] [PubMed] [Google Scholar]
  128. Heyraud F., Matzeit V., Kammann M., Schaefer S., Schell J., Gronenborn B. Identification of the initiation sequence for viral-strand DNA synthesis of wheat dwarf virus. EMBO J. 1993 Nov;12(11):4445–4452. doi: 10.1002/j.1460-2075.1993.tb06130.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  129. Hillman B. I., Carrington J. C., Morris T. J. A defective interfering RNA that contains a mosaic of a plant virus genome. Cell. 1987 Nov 6;51(3):427–433. doi: 10.1016/0092-8674(87)90638-6. [DOI] [PubMed] [Google Scholar]
  130. Hirochika H., Hayashi K. A new strategy to improve a cauliflower mosaic virus vector. Gene. 1991 Sep 15;105(2):239–241. doi: 10.1016/0378-1119(91)90156-6. [DOI] [PubMed] [Google Scholar]
  131. Hohn T., Fütterer J. Transcriptional and translational control of gene expression in cauliflower mosaic virus. Curr Opin Genet Dev. 1992 Feb;2(1):90–96. doi: 10.1016/s0959-437x(05)80328-4. [DOI] [PubMed] [Google Scholar]
  132. Howell S. H., Walker L. L., Dudley R. K. Cloned Cauliflower Mosaic Virus DNA Infects Turnips (Brassica rapa). Science. 1980 Jun 13;208(4449):1265–1267. doi: 10.1126/science.208.4449.1265. [DOI] [PubMed] [Google Scholar]
  133. Hwang D. J., Roberts I. M., Wilson T. M. Expression of tobacco mosaic virus coat protein and assembly of pseudovirus particles in Escherichia coli. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):9067–9071. doi: 10.1073/pnas.91.19.9067. [DOI] [PMC free article] [PubMed] [Google Scholar]
  134. Ilyina T. V., Koonin E. V. Conserved sequence motifs in the initiator proteins for rolling circle DNA replication encoded by diverse replicons from eubacteria, eucaryotes and archaebacteria. Nucleic Acids Res. 1992 Jul 11;20(13):3279–3285. doi: 10.1093/nar/20.13.3279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  135. Jacks T., Madhani H. D., Masiarz F. R., Varmus H. E. Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region. Cell. 1988 Nov 4;55(3):447–458. doi: 10.1016/0092-8674(88)90031-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  136. Jacks T., Varmus H. E. Expression of the Rous sarcoma virus pol gene by ribosomal frameshifting. Science. 1985 Dec 13;230(4731):1237–1242. doi: 10.1126/science.2416054. [DOI] [PubMed] [Google Scholar]
  137. Janda M., Ahlquist P. RNA-dependent replication, transcription, and persistence of brome mosaic virus RNA replicons in S. cerevisiae. Cell. 1993 Mar 26;72(6):961–970. doi: 10.1016/0092-8674(93)90584-d. [DOI] [PubMed] [Google Scholar]
  138. Jobling S. A., Gehrke L. Enhanced translation of chimaeric messenger RNAs containing a plant viral untranslated leader sequence. Nature. 1987 Feb 12;325(6105):622–625. doi: 10.1038/325622a0. [DOI] [PubMed] [Google Scholar]
  139. Johnson P. R., Hamm T. E., Goldstein S., Kitov S., Hirsch V. M. The genetic fate of molecularly cloned simian immunodeficiency virus in experimentally infected macaques. Virology. 1991 Nov;185(1):217–228. doi: 10.1016/0042-6822(91)90769-8. [DOI] [PubMed] [Google Scholar]
  140. Joshi R. L., Joshi V., Ow D. W. BSMV genome mediated expression of a foreign gene in dicot and monocot plant cells. EMBO J. 1990 Sep;9(9):2663–2669. doi: 10.1002/j.1460-2075.1990.tb07451.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  141. Joshi R. L., Ravel J. M., Haenni A. L. Interaction of turnip yellow mosaic virus Val-RNA with eukaryotic elongation factor EF-1 [alpha]. Search for a function. EMBO J. 1986 Jun;5(6):1143–1148. doi: 10.1002/j.1460-2075.1986.tb04339.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  142. Jupin I., Guilley H., Richards K. E., Jonard G. Two proteins encoded by beet necrotic yellow vein virus RNA 3 influence symptom phenotype on leaves. EMBO J. 1992 Feb;11(2):479–488. doi: 10.1002/j.1460-2075.1992.tb05078.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  143. Jupin I., Richards K., Jonard G., Guilley H., Pleij C. W. Mapping sequences required for productive replication of beet necrotic yellow vein virus RNA 3. Virology. 1990 Sep;178(1):273–280. doi: 10.1016/0042-6822(90)90403-e. [DOI] [PubMed] [Google Scholar]
  144. Kamer G., Argos P. Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses. Nucleic Acids Res. 1984 Sep 25;12(18):7269–7282. doi: 10.1093/nar/12.18.7269. [DOI] [PMC free article] [PubMed] [Google Scholar]
  145. Kammann M., Matzeit V., Schmidt B., Schell J., Walden R., Gronenborn B. Geminivirus-based shuttle vectors capable of replication in Escherichia coli and monocotyledonous plant cells. Gene. 1991 Aug 15;104(2):247–252. doi: 10.1016/0378-1119(91)90257-c. [DOI] [PubMed] [Google Scholar]
  146. Kammann M., Schalk H. J., Matzeit V., Schaefer S., Schell J., Gronenborn B. DNA replication of wheat dwarf virus, a geminivirus, requires two cis-acting signals. Virology. 1991 Oct;184(2):786–790. doi: 10.1016/0042-6822(91)90453-i. [DOI] [PubMed] [Google Scholar]
  147. Kao C. C., Ahlquist P. Identification of the domains required for direct interaction of the helicase-like and polymerase-like RNA replication proteins of brome mosaic virus. J Virol. 1992 Dec;66(12):7293–7302. doi: 10.1128/jvi.66.12.7293-7302.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  148. Katagiri F., Lam E., Chua N. H. Two tobacco DNA-binding proteins with homology to the nuclear factor CREB. Nature. 1989 Aug 31;340(6236):727–730. doi: 10.1038/340727a0. [DOI] [PubMed] [Google Scholar]
  149. Kay R., Chan A., Daly M., McPherson J. Duplication of CaMV 35S Promoter Sequences Creates a Strong Enhancer for Plant Genes. Science. 1987 Jun 5;236(4806):1299–1302. doi: 10.1126/science.236.4806.1299. [DOI] [PubMed] [Google Scholar]
  150. Kearney C. M., Donson J., Jones G. E., Dawson W. O. Low level of genetic drift in foreign sequences replicating in an RNA virus in plants. Virology. 1993 Jan;192(1):11–17. doi: 10.1006/viro.1993.1002. [DOI] [PubMed] [Google Scholar]
  151. Kim K. H., Lommel S. A. Identification and analysis of the site of -1 ribosomal frameshifting in red clover necrotic mosaic virus. Virology. 1994 May 1;200(2):574–582. doi: 10.1006/viro.1994.1220. [DOI] [PubMed] [Google Scholar]
  152. Kondrashov A. S. Classification of hypotheses on the advantage of amphimixis. J Hered. 1993 Sep-Oct;84(5):372–387. doi: 10.1093/oxfordjournals.jhered.a111358. [DOI] [PubMed] [Google Scholar]
  153. Kondrashov A. S. Deleterious mutations and the evolution of sexual reproduction. Nature. 1988 Dec 1;336(6198):435–440. doi: 10.1038/336435a0. [DOI] [PubMed] [Google Scholar]
  154. Koonin E. V., Dolja V. V. Evolution and taxonomy of positive-strand RNA viruses: implications of comparative analysis of amino acid sequences. Crit Rev Biochem Mol Biol. 1993;28(5):375–430. doi: 10.3109/10409239309078440. [DOI] [PubMed] [Google Scholar]
  155. Koonin E. V., Ilyina T. V. Computer-assisted dissection of rolling circle DNA replication. Biosystems. 1993;30(1-3):241–268. doi: 10.1016/0303-2647(93)90074-m. [DOI] [PubMed] [Google Scholar]
  156. Koonin E. V. Similarities in RNA helicases. Nature. 1991 Jul 25;352(6333):290–290. doi: 10.1038/352290c0. [DOI] [PubMed] [Google Scholar]
  157. Koonin E. V. The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses. J Gen Virol. 1991 Sep;72(Pt 9):2197–2206. doi: 10.1099/0022-1317-72-9-2197. [DOI] [PubMed] [Google Scholar]
  158. Kozak M. Regulation of translation in eukaryotic systems. Annu Rev Cell Biol. 1992;8:197–225. doi: 10.1146/annurev.cb.08.110192.001213. [DOI] [PubMed] [Google Scholar]
  159. Kujawa A. B., Drugeon G., Hulanicka D., Haenni A. L. Structural requirements for efficient translational frameshifting in the synthesis of the putative viral RNA-dependent RNA polymerase of potato leafroll virus. Nucleic Acids Res. 1993 May 11;21(9):2165–2171. doi: 10.1093/nar/21.9.2165. [DOI] [PMC free article] [PubMed] [Google Scholar]
  160. Kumagai M. H., Donson J., della-Cioppa G., Harvey D., Hanley K., Grill L. K. Cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA. Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1679–1683. doi: 10.1073/pnas.92.5.1679. [DOI] [PMC free article] [PubMed] [Google Scholar]
  161. Kumagai M. H., Turpen T. H., Weinzettl N., della-Cioppa G., Turpen A. M., Donson J., Hilf M. E., Grantham G. L., Dawson W. O., Chow T. P. Rapid, high-level expression of biologically active alpha-trichosanthin in transfected plants by an RNA viral vector. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):427–430. doi: 10.1073/pnas.90.2.427. [DOI] [PMC free article] [PubMed] [Google Scholar]
  162. Lai M. M. RNA recombination in animal and plant viruses. Microbiol Rev. 1992 Mar;56(1):61–79. doi: 10.1128/mr.56.1.61-79.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  163. Lam E., Benfey P. N., Gilmartin P. M., Fang R. X., Chua N. H. Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants. Proc Natl Acad Sci U S A. 1989 Oct;86(20):7890–7894. doi: 10.1073/pnas.86.20.7890. [DOI] [PMC free article] [PubMed] [Google Scholar]
  164. Lam E., Chua N. H. ASF-2: a factor that binds to the cauliflower mosaic virus 35S promoter and a conserved GATA motif in Cab promoters. Plant Cell. 1989 Dec;1(12):1147–1156. doi: 10.1105/tpc.1.12.1147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  165. Laufs J., Wirtz U., Kammann M., Matzeit V., Schaefer S., Schell J., Czernilofsky A. P., Baker B., Gronenborn B. Wheat dwarf virus Ac/Ds vectors: expression and excision of transposable elements introduced into various cereals by a viral replicon. Proc Natl Acad Sci U S A. 1990 Oct;87(19):7752–7756. doi: 10.1073/pnas.87.19.7752. [DOI] [PMC free article] [PubMed] [Google Scholar]
  166. Lazarowitz S. G., Pinder A. J., Damsteegt V. D., Rogers S. G. Maize streak virus genes essential for systemic spread and symptom development. EMBO J. 1989 Apr;8(4):1023–1032. doi: 10.1002/j.1460-2075.1989.tb03469.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  167. Lazarowitz S. G., Wu L. C., Rogers S. G., Elmer J. S. Sequence-specific interaction with the viral AL1 protein identifies a geminivirus DNA replication origin. Plant Cell. 1992 Jul;4(7):799–809. doi: 10.1105/tpc.4.7.799. [DOI] [PMC free article] [PubMed] [Google Scholar]
  168. Laín S., Martín M. T., Riechmann J. L., García J. A. Novel catalytic activity associated with positive-strand RNA virus infection: nucleic acid-stimulated ATPase activity of the plum pox potyvirus helicaselike protein. J Virol. 1991 Jan;65(1):1–6. doi: 10.1128/jvi.65.1.1-6.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  169. Laín S., Riechmann J. L., García J. A. RNA helicase: a novel activity associated with a protein encoded by a positive strand RNA virus. Nucleic Acids Res. 1990 Dec 11;18(23):7003–7006. doi: 10.1093/nar/18.23.7003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  170. Leathers V., Tanguay R., Kobayashi M., Gallie D. R. A phylogenetically conserved sequence within viral 3' untranslated RNA pseudoknots regulates translation. Mol Cell Biol. 1993 Sep;13(9):5331–5347. doi: 10.1128/mcb.13.9.5331. [DOI] [PMC free article] [PubMed] [Google Scholar]
  171. Lehto K., Dawson W. O. Replication, stability, and gene expression of tobacco mosaic virus mutants with a second 30K ORF. Virology. 1990 Mar;175(1):30–40. doi: 10.1016/0042-6822(90)90183-r. [DOI] [PubMed] [Google Scholar]
  172. Lehto K., Grantham G. L., Dawson W. O. Insertion of sequences containing the coat protein subgenomic RNA promoter and leader in front of the tobacco mosaic virus 30K ORF delays its expression and causes defective cell-to-cell movement. Virology. 1990 Jan;174(1):145–157. doi: 10.1016/0042-6822(90)90063-w. [DOI] [PubMed] [Google Scholar]
  173. Levis C., Astier-Manifacier S. The 5' untranslated region of PVY RNA, even located in an internal position, enables initiation of translation. Virus Genes. 1993 Dec;7(4):367–379. doi: 10.1007/BF01703392. [DOI] [PubMed] [Google Scholar]
  174. Li X. H., Carrington J. C. Complementation of tobacco etch potyvirus mutants by active RNA polymerase expressed in transgenic cells. Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):457–461. doi: 10.1073/pnas.92.2.457. [DOI] [PMC free article] [PubMed] [Google Scholar]
  175. Li X. H., Carrington J. C. Nuclear transport of tobacco etch potyviral RNA-dependent RNA polymerase is highly sensitive to sequence alterations. Virology. 1993 Apr;193(2):951–958. doi: 10.1006/viro.1993.1204. [DOI] [PubMed] [Google Scholar]
  176. Litvak S., Tarrago-Litvak L., Chapeville F. Turnip Yellow Mosaic Virus RNA as a Substrate of the Transfer RNA Nucleotidyltransferase II. Incorporation of Cytidine 5'-Monophosphate and Determination of a Short Nucleotide Sequence at the 3' End of the RNA. J Virol. 1973 Feb;11(2):238–242. doi: 10.1128/jvi.11.2.238-242.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  177. Lomonossoff G. P., Butler P. J. Location and encapsidation of the coat protein cistron of tobacco mosaic virus. A bidirectional elongation of the nucleoprotein rod. Eur J Biochem. 1979 Jan 2;93(1):157–164. doi: 10.1111/j.1432-1033.1979.tb12806.x. [DOI] [PubMed] [Google Scholar]
  178. Lomonossoff G. P., Johnson J. E. The synthesis and structure of comovirus capsids. Prog Biophys Mol Biol. 1991;55(2):107–137. doi: 10.1016/0079-6107(91)90003-b. [DOI] [PubMed] [Google Scholar]
  179. Lůcas W. J., Wolf S. Plasmodesmata: the intercellular organelles of green plants. Trends Cell Biol. 1993 Sep;3(9):308–315. doi: 10.1016/0962-8924(93)90013-q. [DOI] [PubMed] [Google Scholar]
  180. Marcos J. F., Beachy R. N. In vitro characterization of a cassette to accumulate multiple proteins through synthesis of a self-processing polypeptide. Plant Mol Biol. 1994 Feb;24(3):495–503. doi: 10.1007/BF00024117. [DOI] [PubMed] [Google Scholar]
  181. Marsh L. E., Dreher T. W., Hall T. C. Mutational analysis of the core and modulator sequences of the BMV RNA3 subgenomic promoter. Nucleic Acids Res. 1988 Feb 11;16(3):981–995. doi: 10.1093/nar/16.3.981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  182. Matthews R. E. Viral taxonomy for the nonvirologist. Annu Rev Microbiol. 1985;39:451–474. doi: 10.1146/annurev.mi.39.100185.002315. [DOI] [PubMed] [Google Scholar]
  183. Matzeit V., Schaefer S., Kammann M., Schalk H. J., Schell J., Gronenborn B. Wheat dwarf virus vectors replicate and express foreign genes in cells of monocotyledonous plants. Plant Cell. 1991 Mar;3(3):247–258. doi: 10.1105/tpc.3.3.247. [DOI] [PMC free article] [PubMed] [Google Scholar]
  184. Medberry S. L., Lockhart B. E., Olszewski N. E. The Commelina yellow mottle virus promoter is a strong promoter in vascular and reproductive tissues. Plant Cell. 1992 Feb;4(2):185–192. doi: 10.1105/tpc.4.2.185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  185. Medberry S. L., Olszewski N. E. Identification of cis elements involved in Commelina yellow mottle virus promoter activity. Plant J. 1993 Apr;3(4):619–626. doi: 10.1046/j.1365-313x.1993.03040619.x. [DOI] [PubMed] [Google Scholar]
  186. Mellon M., Rissler J. Viral recombination in transgenic plants. Science. 1994 Apr 22;264(5158):489–490. [PubMed] [Google Scholar]
  187. Mi S., Stollar V. Both amino acid changes in nsP1 of Sindbis virusLM21 contribute to and are required for efficient expression of the mutant phenotype. Virology. 1990 Oct;178(2):429–434. doi: 10.1016/0042-6822(90)90340-w. [DOI] [PubMed] [Google Scholar]
  188. Mi S., Stollar V. Expression of Sindbis virus nsP1 and methyltransferase activity in Escherichia coli. Virology. 1991 Sep;184(1):423–427. doi: 10.1016/0042-6822(91)90862-6. [DOI] [PubMed] [Google Scholar]
  189. Miller W. A., Bujarski J. J., Dreher T. W., Hall T. C. Minus-strand initiation by brome mosaic virus replicase within the 3' tRNA-like structure of native and modified RNA templates. J Mol Biol. 1986 Feb 20;187(4):537–546. doi: 10.1016/0022-2836(86)90332-3. [DOI] [PubMed] [Google Scholar]
  190. Miller W. A., Dreher T. W., Hall T. C. Synthesis of brome mosaic virus subgenomic RNA in vitro by internal initiation on (-)-sense genomic RNA. Nature. 1985 Jan 3;313(5997):68–70. doi: 10.1038/313068a0. [DOI] [PubMed] [Google Scholar]
  191. Mirzayan C., Wimmer E. Biochemical studies on poliovirus polypeptide 2C: evidence for ATPase activity. Virology. 1994 Feb 15;199(1):176–187. doi: 10.1006/viro.1994.1110. [DOI] [PubMed] [Google Scholar]
  192. Mirzayan C., Wimmer E. Genetic analysis of an NTP-binding motif in poliovirus polypeptide 2C. Virology. 1992 Aug;189(2):547–555. doi: 10.1016/0042-6822(92)90578-d. [DOI] [PubMed] [Google Scholar]
  193. Mori M., Kaido M., Okuno T., Furusawa I. mRNA amplification system by viral replicase in transgenic plants. FEBS Lett. 1993 Dec 20;336(1):171–174. doi: 10.1016/0014-5793(93)81634-c. [DOI] [PubMed] [Google Scholar]
  194. Mori M., Zhang G. H., Kaido M., Okuno T., Furusawa I. Efficient production of human gamma interferon in tobacco protoplasts by genetically engineered brome mosaic virus RNAs. J Gen Virol. 1993 Jul;74(Pt 7):1255–1260. doi: 10.1099/0022-1317-74-7-1255. [DOI] [PubMed] [Google Scholar]
  195. Morozov SYu, Miroshnichenko N. A., Solovyev A. G., Fedorkin O. N., Zelenina D. A., Lukasheva L. I., Karasev A. V., Dolja V. V., Atabekov J. G. Expression strategy of the potato virus X triple gene block. J Gen Virol. 1991 Aug;72(Pt 8):2039–2042. doi: 10.1099/0022-1317-72-8-2039. [DOI] [PubMed] [Google Scholar]
  196. Murphy J. F., Rychlik W., Rhoads R. E., Hunt A. G., Shaw J. G. A tyrosine residue in the small nuclear inclusion protein of tobacco vein mottling virus links the VPg to the viral RNA. J Virol. 1991 Jan;65(1):511–513. doi: 10.1128/jvi.65.1.511-513.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  197. Mushegian A. R., Koonin E. V. Cell-to-cell movement of plant viruses. Insights from amino acid sequence comparisons of movement proteins and from analogies with cellular transport systems. Arch Virol. 1993;133(3-4):239–257. doi: 10.1007/BF01313766. [DOI] [PMC free article] [PubMed] [Google Scholar]
  198. Mushegian A. R., Wolff J. A., Richins R. D., Shepherd R. J. Molecular analysis of the essential and nonessential genetic elements in the genome of peanut chlorotic streak caulimovirus. Virology. 1995 Feb 1;206(2):823–834. doi: 10.1006/viro.1995.1005. [DOI] [PubMed] [Google Scholar]
  199. Nagy P. D., Bujarski J. J. Efficient system of homologous RNA recombination in brome mosaic virus: sequence and structure requirements and accuracy of crossovers. J Virol. 1995 Jan;69(1):131–140. doi: 10.1128/jvi.69.1.131-140.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  200. Nagy P. D., Bujarski J. J. Genetic recombination in brome mosaic virus: effect of sequence and replication of RNA on accumulation of recombinants. J Virol. 1992 Nov;66(11):6824–6828. doi: 10.1128/jvi.66.11.6824-6828.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  201. Nagy P. D., Bujarski J. J. Targeting the site of RNA-RNA recombination in brome mosaic virus with antisense sequences. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6390–6394. doi: 10.1073/pnas.90.14.6390. [DOI] [PMC free article] [PubMed] [Google Scholar]
  202. Namba K., Pattanayek R., Stubbs G. Visualization of protein-nucleic acid interactions in a virus. Refined structure of intact tobacco mosaic virus at 2.9 A resolution by X-ray fiber diffraction. J Mol Biol. 1989 Jul 20;208(2):307–325. doi: 10.1016/0022-2836(89)90391-4. [DOI] [PubMed] [Google Scholar]
  203. Nelson M., Zhang Y., Van Etten J. L. DNA methyltransferases and DNA site-specific endonucleases encoded by chlorella viruses. EXS. 1993;64:186–211. doi: 10.1007/978-3-0348-9118-9_9. [DOI] [PubMed] [Google Scholar]
  204. Noueiry A. O., Lucas W. J., Gilbertson R. L. Two proteins of a plant DNA virus coordinate nuclear and plasmodesmal transport. Cell. 1994 Mar 11;76(5):925–932. doi: 10.1016/0092-8674(94)90366-2. [DOI] [PubMed] [Google Scholar]
  205. Novak J. E., Kirkegaard K. Coupling between genome translation and replication in an RNA virus. Genes Dev. 1994 Jul 15;8(14):1726–1737. doi: 10.1101/gad.8.14.1726. [DOI] [PubMed] [Google Scholar]
  206. Nuss D. L. Biological control of chestnut blight: an example of virus-mediated attenuation of fungal pathogenesis. Microbiol Rev. 1992 Dec;56(4):561–576. doi: 10.1128/mr.56.4.561-576.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  207. Odell J. T., Nagy F., Chua N. H. Identification of DNA sequences required for activity of the cauliflower mosaic virus 35S promoter. 1985 Feb 28-Mar 6Nature. 313(6005):810–812. doi: 10.1038/313810a0. [DOI] [PubMed] [Google Scholar]
  208. Oh C. S., Carrington J. C. Identification of essential residues in potyvirus proteinase HC-Pro by site-directed mutagenesis. Virology. 1989 Dec;173(2):692–699. doi: 10.1016/0042-6822(89)90582-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  209. Okada Y. Molecular assembly of tobacco mosaic virus in vitro. Adv Biophys. 1986;22:95–149. doi: 10.1016/0065-227x(86)90004-3. [DOI] [PubMed] [Google Scholar]
  210. Olszewski N., Hagen G., Guilfoyle T. J. A transcriptionally active, covalently closed minichromosome of cauliflower mosaic virus DNA isolated from infected turnip leaves. Cell. 1982 Jun;29(2):395–402. doi: 10.1016/0092-8674(82)90156-8. [DOI] [PubMed] [Google Scholar]
  211. Ow D. W., Jacobs J. D., Howell S. H. Functional regions of the cauliflower mosaic virus 35S RNA promoter determined by use of the firefly luciferase gene as a reporter of promoter activity. Proc Natl Acad Sci U S A. 1987 Jul;84(14):4870–4874. doi: 10.1073/pnas.84.14.4870. [DOI] [PMC free article] [PubMed] [Google Scholar]
  212. Pacha R. F., Ahlquist P. Substantial portions of the 5' and intercistronic noncoding regions of cowpea chlorotic mottle virus RNA3 are dispensable for systemic infection but influence viral competitiveness and infection pathology. Virology. 1992 Mar;187(1):298–307. doi: 10.1016/0042-6822(92)90318-j. [DOI] [PubMed] [Google Scholar]
  213. Pascal E., Goodlove P. E., Wu L. C., Lazarowitz S. G. Transgenic tobacco plants expressing the geminivirus BL1 protein exhibit symptoms of viral disease. Plant Cell. 1993 Jul;5(7):795–807. doi: 10.1105/tpc.5.7.795. [DOI] [PMC free article] [PubMed] [Google Scholar]
  214. Pathak V. K., Temin H. M. Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations. Proc Natl Acad Sci U S A. 1990 Aug;87(16):6019–6023. doi: 10.1073/pnas.87.16.6019. [DOI] [PMC free article] [PubMed] [Google Scholar]
  215. Pelham H. R. Leaky UAG termination codon in tobacco mosaic virus RNA. Nature. 1978 Mar 30;272(5652):469–471. doi: 10.1038/272469a0. [DOI] [PubMed] [Google Scholar]
  216. Pelletier J., Sonenberg N. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature. 1988 Jul 28;334(6180):320–325. doi: 10.1038/334320a0. [DOI] [PubMed] [Google Scholar]
  217. Pennington R. E., Melcher U. In planta deletion of DNA inserts from the large intergenic region of cauliflower mosaic virus DNA. Virology. 1993 Jan;192(1):188–196. doi: 10.1006/viro.1993.1021. [DOI] [PubMed] [Google Scholar]
  218. Perrino F. W., Preston B. D., Sandell L. L., Loeb L. A. Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. Proc Natl Acad Sci U S A. 1989 Nov;86(21):8343–8347. doi: 10.1073/pnas.86.21.8343. [DOI] [PMC free article] [PubMed] [Google Scholar]
  219. Pilipenko E. V., Gmyl A. P., Maslova S. V., Svitkin Y. V., Sinyakov A. N., Agol V. I. Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA. Cell. 1992 Jan 10;68(1):119–131. doi: 10.1016/0092-8674(92)90211-t. [DOI] [PubMed] [Google Scholar]
  220. Pinck M., Yot P., Chapeville F., Duranton H. M. Enzymatic binding of valine to the 3' end of TYMV-RNA. Nature. 1970 Jun 6;226(5249):954–956. doi: 10.1038/226954a0. [DOI] [PubMed] [Google Scholar]
  221. Plant A. L., Covey S. N., Grierson D. Detection of a subgenomic mRNA for gene V, the putative reverse transcriptase gene of cauliflower mosaic virus. Nucleic Acids Res. 1985 Dec 9;13(23):8305–8321. doi: 10.1093/nar/13.23.8305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  222. Pleij C. W. Pseudoknots: a new motif in the RNA game. Trends Biochem Sci. 1990 Apr;15(4):143–147. doi: 10.1016/0968-0004(90)90214-v. [DOI] [PubMed] [Google Scholar]
  223. Pogue G. P., Hall T. C. The requirement for a 5' stem-loop structure in brome mosaic virus replication supports a new model for viral positive-strand RNA initiation. J Virol. 1992 Feb;66(2):674–684. doi: 10.1128/jvi.66.2.674-684.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  224. Pogue G. P., Marsh L. E., Connell J. P., Hall T. C. Requirement for ICR-like sequences in the replication of brome mosaic virus genomic RNA. Virology. 1992 Jun;188(2):742–753. doi: 10.1016/0042-6822(92)90529-x. [DOI] [PubMed] [Google Scholar]
  225. Pooggin M. M., Skryabin K. G. The 5'-untranslated leader sequence of potato virus X RNA enhances the expression of a heterologous gene in vivo. Mol Gen Genet. 1992 Aug;234(2):329–331. doi: 10.1007/BF00283854. [DOI] [PubMed] [Google Scholar]
  226. Porta C., Spall V. E., Loveland J., Johnson J. E., Barker P. J., Lomonossoff G. P. Development of cowpea mosaic virus as a high-yielding system for the presentation of foreign peptides. Virology. 1994 Aug 1;202(2):949–955. doi: 10.1006/viro.1994.1417. [DOI] [PubMed] [Google Scholar]
  227. Preston B. D., Poiesz B. J., Loeb L. A. Fidelity of HIV-1 reverse transcriptase. Science. 1988 Nov 25;242(4882):1168–1171. doi: 10.1126/science.2460924. [DOI] [PubMed] [Google Scholar]
  228. Prüfer D., Tacke E., Schmitz J., Kull B., Kaufmann A., Rohde W. Ribosomal frameshifting in plants: a novel signal directs the -1 frameshift in the synthesis of the putative viral replicase of potato leafroll luteovirus. EMBO J. 1992 Mar;11(3):1111–1117. doi: 10.1002/j.1460-2075.1992.tb05151.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  229. Pulsinelli G. A., Temin H. M. High rate of mismatch extension during reverse transcription in a single round of retrovirus replication. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9490–9494. doi: 10.1073/pnas.91.20.9490. [DOI] [PMC free article] [PubMed] [Google Scholar]
  230. Quadt R., Kao C. C., Browning K. S., Hershberger R. P., Ahlquist P. Characterization of a host protein associated with brome mosaic virus RNA-dependent RNA polymerase. Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1498–1502. doi: 10.1073/pnas.90.4.1498. [DOI] [PMC free article] [PubMed] [Google Scholar]
  231. Raffo A. J., Dawson W. O. Construction of tobacco mosaic virus subgenomic replicons that are replicated and spread systemically in tobacco plants. Virology. 1991 Sep;184(1):277–289. doi: 10.1016/0042-6822(91)90844-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  232. Rao A. L., Hall T. C. Requirement for a viral trans-acting factor encoded by brome mosaic virus RNA-2 provides strong selection in vivo for functional recombinants. J Virol. 1990 May;64(5):2437–2441. doi: 10.1128/jvi.64.5.2437-2441.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  233. Restrepo-Hartwig M. A., Carrington J. C. Regulation of nuclear transport of a plant potyvirus protein by autoproteolysis. J Virol. 1992 Sep;66(9):5662–5666. doi: 10.1128/jvi.66.9.5662-5666.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  234. Restrepo-Hartwig M. A., Carrington J. C. The tobacco etch potyvirus 6-kilodalton protein is membrane associated and involved in viral replication. J Virol. 1994 Apr;68(4):2388–2397. doi: 10.1128/jvi.68.4.2388-2397.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  235. Restrepo M. A., Freed D. D., Carrington J. C. Nuclear transport of plant potyviral proteins. Plant Cell. 1990 Oct;2(10):987–998. doi: 10.1105/tpc.2.10.987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  236. Ricchetti M., Buc H. E. coli DNA polymerase I as a reverse transcriptase. EMBO J. 1993 Feb;12(2):387–396. doi: 10.1002/j.1460-2075.1993.tb05670.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  237. Roberts J. D., Bebenek K., Kunkel T. A. The accuracy of reverse transcriptase from HIV-1. Science. 1988 Nov 25;242(4882):1171–1173. doi: 10.1126/science.2460925. [DOI] [PubMed] [Google Scholar]
  238. Rochon D. M., Johnston J. C. Infectious transcripts from cloned cucumber necrosis virus cDNA: evidence for a bifunctional subgenomic mRNA. Virology. 1991 Apr;181(2):656–665. doi: 10.1016/0042-6822(91)90899-m. [DOI] [PubMed] [Google Scholar]
  239. Rochon D. M. Rapid de novo generation of defective interfering RNA by cucumber necrosis virus mutants that do not express the 20-kDa nonstructural protein. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11153–11157. doi: 10.1073/pnas.88.24.11153. [DOI] [PMC free article] [PubMed] [Google Scholar]
  240. Rogers S. G., Bisaro D. M., Horsch R. B., Fraley R. T., Hoffmann N. L., Brand L., Elmer J. S., Lloyd A. M. Tomato golden mosaic virus A component DNA replicates autonomously in transgenic plants. Cell. 1986 May 23;45(4):593–600. doi: 10.1016/0092-8674(86)90291-6. [DOI] [PubMed] [Google Scholar]
  241. Rohde W., Becker D., Randles J. W. The promoter of coconut foliar decay-associated circular single-stranded DNA directs phloem-specific reporter gene expression in transgenic tobacco. Plant Mol Biol. 1995 Feb;27(3):623–628. doi: 10.1007/BF00019328. [DOI] [PubMed] [Google Scholar]
  242. Rohde W., Randles J. W., Langridge P., Hanold D. Nucleotide sequence of a circular single-stranded DNA associated with coconut foliar decay virus. Virology. 1990 Jun;176(2):648–651. doi: 10.1016/0042-6822(90)90038-s. [DOI] [PubMed] [Google Scholar]
  243. Romero J., Huang Q., Pogany J., Bujarski J. J. Characterization of defective interfering RNA components that increase symptom severity of broad bean mottle virus infections. Virology. 1993 Jun;194(2):576–584. doi: 10.1006/viro.1993.1297. [DOI] [PubMed] [Google Scholar]
  244. Rommens C. M., Salmeron J. M., Baulcombe D. C., Staskawicz B. J. Use of a gene expression system based on potato virus X to rapidly identify and characterize a tomato Pto homolog that controls fenthion sensitivity. Plant Cell. 1995 Mar;7(3):249–257. doi: 10.1105/tpc.7.3.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
  245. Roossinck M. J., Sleat D., Palukaitis P. Satellite RNAs of plant viruses: structures and biological effects. Microbiol Rev. 1992 Jun;56(2):265–279. doi: 10.1128/mr.56.2.265-279.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  246. Rothnie H. M., Chapdelaine Y., Hohn T. Pararetroviruses and retroviruses: a comparative review of viral structure and gene expression strategies. Adv Virus Res. 1994;44:1–67. doi: 10.1016/s0065-3527(08)60327-9. [DOI] [PubMed] [Google Scholar]
  247. Rothnie H. M., Reid J., Hohn T. The contribution of AAUAAA and the upstream element UUUGUA to the efficiency of mRNA 3'-end formation in plants. EMBO J. 1994 May 1;13(9):2200–2210. doi: 10.1002/j.1460-2075.1994.tb06497.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  248. Rozanov M. N., Koonin E. V., Gorbalenya A. E. Conservation of the putative methyltransferase domain: a hallmark of the 'Sindbis-like' supergroup of positive-strand RNA viruses. J Gen Virol. 1992 Aug;73(Pt 8):2129–2134. doi: 10.1099/0022-1317-73-8-2129. [DOI] [PubMed] [Google Scholar]
  249. Rubino L., Carrington J. C., Russo M. Biologically active cymbidium ringspot virus satellite RNA in transgenic plants suppresses accumulation of DI RNA. Virology. 1992 Jun;188(2):429–437. doi: 10.1016/0042-6822(92)90496-c. [DOI] [PubMed] [Google Scholar]
  250. Ryabova L. A., Torgashov A. F., Kurnasov O. V., Bubunenko M. G., Spirin A. S. The 3'-terminal untranslated region of alfalfa mosaic virus RNA 4 facilitates the RNA entry into translation in a cell-free system. FEBS Lett. 1993 Jul 12;326(1-3):264–266. doi: 10.1016/0014-5793(93)81804-9. [DOI] [PubMed] [Google Scholar]
  251. Ryabova L., Volianik E., Kurnasov O., Spirin A., Wu Y., Kramer F. R. Coupled replication-translation of amplifiable messenger RNA. A cell-free protein synthesis system that mimics viral infection. J Biol Chem. 1994 Jan 14;269(2):1501–1505. [PubMed] [Google Scholar]
  252. Rüth J., Hirt H., Schweyen R. J. The cauliflower mosaic virus 35S promoter is regulated by cAMP in Saccharomyces cerevisiae. Mol Gen Genet. 1992 Nov;235(2-3):365–372. doi: 10.1007/BF00279382. [DOI] [PubMed] [Google Scholar]
  253. Sacher R., French R., Ahlquist P. Hybrid brome mosaic virus RNAs express and are packaged in tobacco mosaic virus coat protein in vivo. Virology. 1988 Nov;167(1):15–24. doi: 10.1016/0042-6822(88)90049-9. [DOI] [PubMed] [Google Scholar]
  254. Sachs A., Wahle E. Poly(A) tail metabolism and function in eucaryotes. J Biol Chem. 1993 Nov 5;268(31):22955–22958. [PubMed] [Google Scholar]
  255. Sanfaçon H. Analysis of figwort mosaic virus (plant pararetrovirus) polyadenylation signal. Virology. 1994 Jan;198(1):39–49. doi: 10.1006/viro.1994.1006. [DOI] [PubMed] [Google Scholar]
  256. Sanfaçon H., Hohn T. Proximity to the promoter inhibits recognition of cauliflower mosaic virus polyadenylation signal. Nature. 1990 Jul 5;346(6279):81–84. doi: 10.1038/346081a0. [DOI] [PubMed] [Google Scholar]
  257. Sanfaçon H., Wieczorek A. Analysis of cauliflower mosaic virus RNAs in Brassica species showing a range of susceptibility to infection. Virology. 1992 Sep;190(1):30–39. doi: 10.1016/0042-6822(92)91189-2. [DOI] [PubMed] [Google Scholar]
  258. Sanger M., Daubert S., Goodman R. M. Characteristics of a strong promoter from figwort mosaic virus: comparison with the analogous 35S promoter from cauliflower mosaic virus and the regulated mannopine synthase promoter. Plant Mol Biol. 1990 Mar;14(3):433–443. doi: 10.1007/BF00028779. [DOI] [PubMed] [Google Scholar]
  259. Sankar S., Porter A. G. Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I. J Biol Chem. 1992 May 15;267(14):10168–10176. [PubMed] [Google Scholar]
  260. Schalk H. J., Matzeit V., Schiller B., Schell J., Gronenborn B. Wheat dwarf virus, a geminivirus of graminaceous plants needs splicing for replication. EMBO J. 1989 Feb;8(2):359–364. doi: 10.1002/j.1460-2075.1989.tb03385.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  261. Scholthof H. B., Wu F. C., Richins R. D., Shepherd R. J. A naturally occurring deletion mutant of figwort mosaic virus (caulimovirus) is generated by RNA splicing. Virology. 1991 Sep;184(1):290–298. doi: 10.1016/0042-6822(91)90845-3. [DOI] [PubMed] [Google Scholar]
  262. Shah D. M., Horsch R. B., Klee H. J., Kishore G. M., Winter J. A., Tumer N. E., Hironaka C. M., Sanders P. R., Gasser C. S., Aykent S., Siegel N. R., Rogers S. G., Fraley R. T. Engineering herbicide tolerance in transgenic plants. Science. 1986 Jul 25;233(4762):478–481. doi: 10.1126/science.233.4762.478. [DOI] [PubMed] [Google Scholar]
  263. Sheldon C. C., Symons R. H. Is hammerhead self-cleavage involved in the replication of a virusoid in vivo? Virology. 1993 Jun;194(2):463–474. doi: 10.1006/viro.1993.1285. [DOI] [PubMed] [Google Scholar]
  264. Shen W. H., Hohn B. Mutational analysis of the small intergenic region of maize streak virus. Virology. 1991 Aug;183(2):721–730. doi: 10.1016/0042-6822(91)91001-w. [DOI] [PubMed] [Google Scholar]
  265. Shen W. H., Hohn B. Vectors based on maize streak virus can replicate to high copy numbers in maize plants. J Gen Virol. 1995 Apr;76(Pt 4):965–969. doi: 10.1099/0022-1317-76-4-965. [DOI] [PubMed] [Google Scholar]
  266. Shintaku M. H., Zhang L., Palukaitis P. A single amino acid substitution in the coat protein of cucumber mosaic virus induces chlorosis in tobacco. Plant Cell. 1992 Jul;4(7):751–757. doi: 10.1105/tpc.4.7.751. [DOI] [PMC free article] [PubMed] [Google Scholar]
  267. Skuzeski J. M., Nichols L. M., Gesteland R. F. Analysis of leaky viral translation termination codons in vivo by transient expression of improved beta-glucuronidase vectors. Plant Mol Biol. 1990 Jul;15(1):65–79. doi: 10.1007/BF00017725. [DOI] [PubMed] [Google Scholar]
  268. Skuzeski J. M., Nichols L. M., Gesteland R. F., Atkins J. F. The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons. J Mol Biol. 1991 Mar 20;218(2):365–373. doi: 10.1016/0022-2836(91)90718-l. [DOI] [PubMed] [Google Scholar]
  269. Sleat D. E., Gallie D. R., Watts J. W., Deom C. M., Turner P. C., Beachy R. N., Wilson T. M. Selective recovery of foreign gene transcripts as virus-like particles in TMV-infected transgenic tobaccos. Nucleic Acids Res. 1988 Apr 25;16(8):3127–3140. doi: 10.1093/nar/16.8.3127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  270. Smirnyagina E., Hsu Y. H., Chua N., Ahlquist P. Second-site mutations in the brome mosaic virus RNA3 intercistronic region partially suppress a defect in coat protein mRNA transcription. Virology. 1994 Feb;198(2):427–436. doi: 10.1006/viro.1994.1054. [DOI] [PubMed] [Google Scholar]
  271. Smith G. P. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science. 1985 Jun 14;228(4705):1315–1317. doi: 10.1126/science.4001944. [DOI] [PubMed] [Google Scholar]
  272. Smith T. A., Kohorn B. D. Direct selection for sequences encoding proteases of known specificity. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5159–5162. doi: 10.1073/pnas.88.12.5159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  273. Sonenberg N. Picornavirus RNA translation continues to surprise. Trends Genet. 1991 Apr;7(4):105–106. doi: 10.1016/0168-9525(91)90440-2. [DOI] [PubMed] [Google Scholar]
  274. Stanley J. Analysis of African cassava mosaic virus recombinants suggests strand nicking occurs within the conserved nonanucleotide motif during the initiation of rolling circle DNA replication. Virology. 1995 Jan 10;206(1):707–712. doi: 10.1016/s0042-6822(95)80093-x. [DOI] [PubMed] [Google Scholar]
  275. Steinhauer D. A., Domingo E., Holland J. J. Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase. Gene. 1992 Dec 15;122(2):281–288. doi: 10.1016/0378-1119(92)90216-c. [DOI] [PubMed] [Google Scholar]
  276. Stenger D. C., Revington G. N., Stevenson M. C., Bisaro D. M. Replicational release of geminivirus genomes from tandemly repeated copies: evidence for rolling-circle replication of a plant viral DNA. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8029–8033. doi: 10.1073/pnas.88.18.8029. [DOI] [PMC free article] [PubMed] [Google Scholar]
  277. Sternberg N., Hoess R. H. Display of peptides and proteins on the surface of bacteriophage lambda. Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1609–1613. doi: 10.1073/pnas.92.5.1609. [DOI] [PMC free article] [PubMed] [Google Scholar]
  278. Sugiyama Y., Hamamoto H., Takemoto S., Watanabe Y., Okada Y. Systemic production of foreign peptides on the particle surface of tobacco mosaic virus. FEBS Lett. 1995 Feb 13;359(2-3):247–250. doi: 10.1016/0014-5793(95)00054-d. [DOI] [PubMed] [Google Scholar]
  279. Sunter G., Bisaro D. M. Transactivation of geminivirus AR1 and BR1 gene expression by the viral AL2 gene product occurs at the level of transcription. Plant Cell. 1992 Oct;4(10):1321–1331. doi: 10.1105/tpc.4.10.1321. [DOI] [PMC free article] [PubMed] [Google Scholar]
  280. Sunter G., Hartitz M. D., Bisaro D. M. Tomato golden mosaic virus leftward gene expression: autoregulation of geminivirus replication protein. Virology. 1993 Jul;195(1):275–280. doi: 10.1006/viro.1993.1374. [DOI] [PubMed] [Google Scholar]
  281. Takamatsu N., Ishikawa M., Meshi T., Okada Y. Expression of bacterial chloramphenicol acetyltransferase gene in tobacco plants mediated by TMV-RNA. EMBO J. 1987 Feb;6(2):307–311. doi: 10.1002/j.1460-2075.1987.tb04755.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  282. Temin H. M. Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation. Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):6900–6903. doi: 10.1073/pnas.90.15.6900. [DOI] [PMC free article] [PubMed] [Google Scholar]
  283. Teterina N. L., Kean K. M., Gorbalenya A. E., Agol V. I., Girard M. Analysis of the functional significance of amino acid residues in the putative NTP-binding pattern of the poliovirus 2C protein. J Gen Virol. 1992 Aug;73(Pt 8):1977–1986. doi: 10.1099/0022-1317-73-8-1977. [DOI] [PubMed] [Google Scholar]
  284. Thömmes P., Osman T. A., Hayes R. J., Buck K. W. TGMV replication protein AL1 preferentially binds to single-stranded DNA from the common region. FEBS Lett. 1993 Mar 15;319(1-2):95–99. doi: 10.1016/0014-5793(93)80044-u. [DOI] [PubMed] [Google Scholar]
  285. Timmer R. T., Benkowski L. A., Schodin D., Lax S. R., Metz A. M., Ravel J. M., Browning K. S. The 5' and 3' untranslated regions of satellite tobacco necrosis virus RNA affect translational efficiency and dependence on a 5' cap structure. J Biol Chem. 1993 May 5;268(13):9504–9510. [PubMed] [Google Scholar]
  286. Timmermans M. C., Das O. P., Messing J. Trans replication and high copy numbers of wheat dwarf virus vectors in maize cells. Nucleic Acids Res. 1992 Aug 11;20(15):4047–4054. doi: 10.1093/nar/20.15.4047. [DOI] [PMC free article] [PubMed] [Google Scholar]
  287. Tomashevskaya O. L., Solovyev A. G., Karpova O. V., Fedorkin O. N., Rodionova N. P., Morozov SYu, Atabekov J. G. Effects of sequence elements in the potato virus X RNA 5' non-translated alpha beta-leader on its translation enhancing activity. J Gen Virol. 1993 Dec;74(Pt 12):2717–2724. doi: 10.1099/0022-1317-74-12-2717. [DOI] [PubMed] [Google Scholar]
  288. Tsai C. H., Dreher T. W. Increased viral yield and symptom severity result from a single amino acid substitution in the turnip yellow mosaic virus movement protein. Mol Plant Microbe Interact. 1993 May-Jun;6(3):268–273. doi: 10.1094/mpmi-6-268. [DOI] [PubMed] [Google Scholar]
  289. Tsai C. H., Dreher T. W. Turnip yellow mosaic virus RNAs with anticodon loop substitutions that result in decreased valylation fail to replicate efficiently. J Virol. 1991 Jun;65(6):3060–3067. doi: 10.1128/jvi.65.6.3060-3067.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  290. Turner D. R., Joyce L. E., Butler P. J. The tobacco mosaic virus assembly origin RNA. Functional characteristics defined by directed mutagenesis. J Mol Biol. 1988 Oct 5;203(3):531–547. doi: 10.1016/0022-2836(88)90190-8. [DOI] [PubMed] [Google Scholar]
  291. Turner D. R., McGuigan C. J., Butler P. J. Assembly of hybrid RNAs with tobacco mosaic virus coat protein. Evidence for incorporation of disks in 5'-elongation along the major RNA tail. J Mol Biol. 1989 Oct 5;209(3):407–422. doi: 10.1016/0022-2836(89)90006-5. [DOI] [PubMed] [Google Scholar]
  292. Turpen T. H., Reinl S. J., Charoenvit Y., Hoffman S. L., Fallarme V., Grill L. K. Malarial epitopes expressed on the surface of recombinant tobacco mosaic virus. Biotechnology (N Y) 1995 Jan;13(1):53–57. doi: 10.1038/nbt0195-53. [DOI] [PubMed] [Google Scholar]
  293. Turpen T. H., Turpen A. M., Weinzettl N., Kumagai M. H., Dawson W. O. Transfection of whole plants from wounds inoculated with Agrobacterium tumefaciens containing cDNA of tobacco mosaic virus. J Virol Methods. 1993 May;42(2-3):227–239. doi: 10.1016/0166-0934(93)90035-p. [DOI] [PubMed] [Google Scholar]
  294. Ugaki M., Ueda T., Timmermans M. C., Vieira J., Elliston K. O., Messing J. Replication of a geminivirus derived shuttle vector in maize endosperm cells. Nucleic Acids Res. 1991 Jan 25;19(2):371–377. doi: 10.1093/nar/19.2.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  295. Vaden V. R., Melcher U. Recombination sites in cauliflower mosaic virus DNAs: implications for mechanisms of recombination. Virology. 1990 Aug;177(2):717–726. doi: 10.1016/0042-6822(90)90538-3. [DOI] [PubMed] [Google Scholar]
  296. Van Bokhoven H., Le Gall O., Kasteel D., Verver J., Wellink J., Van Kammen A. B. Cis- and trans-acting elements in cowpea mosaic virus RNA replication. Virology. 1993 Aug;195(2):377–386. doi: 10.1006/viro.1993.1387. [DOI] [PubMed] [Google Scholar]
  297. Verchot J., Herndon K. L., Carrington J. C. Mutational analysis of the tobacco etch potyviral 35-kDa proteinase: identification of essential residues and requirements for autoproteolysis. Virology. 1992 Sep;190(1):298–306. doi: 10.1016/0042-6822(92)91216-h. [DOI] [PubMed] [Google Scholar]
  298. Verver J., Le Gall O., van Kammen A., Wellink J. The sequence between nucleotides 161 and 512 of cowpea mosaic virus M RNA is able to support internal initiation of translation in vitro. J Gen Virol. 1991 Oct;72(Pt 10):2339–2345. doi: 10.1099/0022-1317-72-10-2339. [DOI] [PubMed] [Google Scholar]
  299. Wahle E., Keller W. The biochemistry of 3'-end cleavage and polyadenylation of messenger RNA precursors. Annu Rev Biochem. 1992;61:419–440. doi: 10.1146/annurev.bi.61.070192.002223. [DOI] [PubMed] [Google Scholar]
  300. Waigmann E., Lucas W. J., Citovsky V., Zambryski P. Direct functional assay for tobacco mosaic virus cell-to-cell movement protein and identification of a domain involved in increasing plasmodesmal permeability. Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1433–1437. doi: 10.1073/pnas.91.4.1433. [DOI] [PMC free article] [PubMed] [Google Scholar]
  301. Walden R. M., Howell S. H. Intergenomic recombination events among pairs of defective cauliflower mosaic virus genomes in plants. J Mol Appl Genet. 1982;1(5):447–456. [PubMed] [Google Scholar]
  302. Ward A., Etessami P., Stanley J. Expression of a bacterial gene in plants mediated by infectious geminivirus DNA. EMBO J. 1988 Jun;7(6):1583–1587. doi: 10.1002/j.1460-2075.1988.tb02983.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  303. Weiland J. J., Dreher T. W. Cis-preferential replication of the turnip yellow mosaic virus RNA genome. Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6095–6099. doi: 10.1073/pnas.90.13.6095. [DOI] [PMC free article] [PubMed] [Google Scholar]
  304. Weiland J. J., Dreher T. W. Infectious TYMV RNA from cloned cDNA: effects in vitro and in vivo of point substitutions in the initiation codons of two extensively overlapping ORFs. Nucleic Acids Res. 1989 Jun 26;17(12):4675–4687. doi: 10.1093/nar/17.12.4675. [DOI] [PMC free article] [PubMed] [Google Scholar]
  305. Wengler G., Wengler G. The NS 3 nonstructural protein of flaviviruses contains an RNA triphosphatase activity. Virology. 1993 Nov;197(1):265–273. doi: 10.1006/viro.1993.1587. [DOI] [PubMed] [Google Scholar]
  306. Wertz G. W., Melero J. A. Workshop on 'reverse genetics of negative stranded RNA viruses' sponsored by the Juan March Institute, Madrid, Spain. Virus Res. 1993 Nov;30(2):215–219. doi: 10.1016/0168-1702(93)90008-b. [DOI] [PubMed] [Google Scholar]
  307. White K. A., Morris T. J. Nonhomologous RNA recombination in tombusviruses: generation and evolution of defective interfering RNAs by stepwise deletions. J Virol. 1994 Jan;68(1):14–24. doi: 10.1128/jvi.68.1.14-24.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  308. White K. A., Morris T. J. Recombination between defective tombusvirus RNAs generates functional hybrid genomes. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3642–3646. doi: 10.1073/pnas.91.9.3642. [DOI] [PMC free article] [PubMed] [Google Scholar]
  309. Wilde R. J., Cooke S. E., Brammar W. J., Schuch W. Control of gene expression in plant cells using a 434:VP16 chimeric protein. Plant Mol Biol. 1994 Jan;24(2):381–388. doi: 10.1007/BF00020175. [DOI] [PubMed] [Google Scholar]
  310. Wills N. M., Gesteland R. F., Atkins J. F. Pseudoknot-dependent read-through of retroviral gag termination codons: importance of sequences in the spacer and loop 2. EMBO J. 1994 Sep 1;13(17):4137–4144. doi: 10.1002/j.1460-2075.1994.tb06731.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  311. Wilson T. M. Strategies to protect crop plants against viruses: pathogen-derived resistance blossoms. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3134–3141. doi: 10.1073/pnas.90.8.3134. [DOI] [PMC free article] [PubMed] [Google Scholar]
  312. Wimmer E., Hellen C. U., Cao X. Genetics of poliovirus. Annu Rev Genet. 1993;27:353–436. doi: 10.1146/annurev.ge.27.120193.002033. [DOI] [PubMed] [Google Scholar]
  313. Zerfass K., Beier H. Pseudouridine in the anticodon G psi A of plant cytoplasmic tRNA(Tyr) is required for UAG and UAA suppression in the TMV-specific context. Nucleic Acids Res. 1992 Nov 25;20(22):5911–5918. doi: 10.1093/nar/20.22.5911. [DOI] [PMC free article] [PubMed] [Google Scholar]
  314. Zhan X., Richardson K. A., Haley A., Morris B. A. The activity of the coat protein promoter of chloris striate mosaic virus is enhanced by its own and C1-C2 gene products. Virology. 1993 Mar;193(1):498–502. doi: 10.1006/viro.1993.1153. [DOI] [PubMed] [Google Scholar]
  315. Zijlstra C., Hohn T. Cauliflower Mosaic Virus Gene VI Controls Translation from Dicistronic Expression Units in Transgenic Arabidopsis Plants. Plant Cell. 1992 Dec;4(12):1471–1484. doi: 10.1105/tpc.4.12.1471. [DOI] [PMC free article] [PubMed] [Google Scholar]
  316. de Carvalho F., Gheysen G., Kushnir S., Van Montagu M., Inzé D., Castresana C. Suppression of beta-1,3-glucanase transgene expression in homozygous plants. EMBO J. 1992 Jul;11(7):2595–2602. doi: 10.1002/j.1460-2075.1992.tb05324.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  317. ten Dam E., Brierley I., Inglis S., Pleij C. Identification and analysis of the pseudoknot-containing gag-pro ribosomal frameshift signal of simian retrovirus-1. Nucleic Acids Res. 1994 Jun 25;22(12):2304–2310. doi: 10.1093/nar/22.12.2304. [DOI] [PMC free article] [PubMed] [Google Scholar]
  318. van Lent J., Storms M., van der Meer F., Wellink J., Goldbach R. Tubular structures involved in movement of cowpea mosaic virus are also formed in infected cowpea protoplasts. J Gen Virol. 1991 Nov;72(Pt 11):2615–2623. doi: 10.1099/0022-1317-72-11-2615. [DOI] [PubMed] [Google Scholar]
  319. van der Kuyl A. C., Neeleman L., Bol J. F. Deletion analysis of cis- and trans-acting elements involved in replication of alfalfa mosaic virus RNA 3 in vivo. Virology. 1991 Aug;183(2):687–694. doi: 10.1016/0042-6822(91)90997-p. [DOI] [PubMed] [Google Scholar]

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