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| Model A | Model B | Model C | Model D | Model E | Result | |
|---|---|---|---|---|---|---|
| c-c′ | + | − | + | + | + | − |
| c-c′′(ΔTM1) | − | + | + | + | + | + |
| c′-c | − | + | + | + | + | + |
| c′-c′′(ΔTM1) | + | − | − | − | − | − |
| c′′(ΔTM1)-c | + | − | + | + | + | − |
| c′′(ΔTM1)-c′ | − | + | − | − | − | + |
“+” indicates the proteolipid ring shown in the corresponding model in Fig. 2 can be formed from the fusion construct indicated whereas “−” indicates the ring cannot be formed.
