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. 2003 Jul 1;89(1):152–157. doi: 10.1038/sj.bjc.6601070

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Copyright © 2003 Cancer Research UK

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Immunohistochemical findings in a Dukes' A carcinoma associated with SA. The carcinoma invaded the submucosal layer. In (A), focal nuclear staining of cells for β-catenin is detected; and cytoplasmic staining for β-catenin is observed in the carcinomatous epithelium of this mixed-type SA. In (B), neither nuclear nor cytoplasmic staining for β-catenin is found in the adjacent serrated epithelium.