Table 3. Observed cases (Obs) of selected cancers, SIR and corresponding 95% CI among people with HIV or AIDS by gender, age group, and HIV exposure category, Italy, 1985–1998.
Gender |
Age group |
HIV exposure category |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Men |
Women |
15–34 |
35–69 |
IDU |
Other |
|||||||
SIR | SIR | SIR | SIR | SIR | SIR | |||||||
ICD10–cancer type or site | Obs | (95% CI) | Obs | (95% CI) | Obs | (95% CI) | Obs | (95% CI) | Obs | (95% CI) | Obs | (95% CI) |
C46: KS | 483 | 1696 | 42 | 2717 | 228 | 1218 | 297 | 2628 | 115 | 557 | 410a | 4369 |
(1548–1854) | (1957–3675) | (1065–1387) | (2337–2945) | (460–669) | (3956–4813) | |||||||
C82–C85: NHL | 350 | 321 | 99 | 538 | 268 | 417 | 181 | 286 | 247 | 335 | 202 | 376 |
(288–356) | (437–655) | (369–470) | (246–331) | (294–379) | (326–432) | |||||||
C53: ICC | — | — | 18 | 21.8 | 8 | 23.4 | 10 | 20.7 | 11 | 24.0 | 7 | 19.1 |
— | (12.9–34.6) | (10.0–46.4) | (9.9–38.2) | (11.9–43.1) | (7.6–39.6) | |||||||
C21: anus | 5 | 35.1 | 1 | 27.6 | 1 | 31.3 | 5 | 34.1 | 2 | 33.6 | 4b | 33.6 |
(11.1–82.5) | (0.0–158.3) | (0.0–179.3) | (10.8–80.2) | (3.2–123.6) | (8.7–86.8) | |||||||
C33, C34: trachea and lung | 19 | 2.2 | 3 | 8.7 | 6 | 19.4 | 16 | 1.8 | 11 | 9.4 | 11 | 1.4 |
(1.3–3.4) | (1.6–25.9) | (7.0–42.4) | (1.0–3.0) | (4.6–16.8) | (0.7–2.5) | |||||||
C44: skin (nonmelanoma) | 13 | 1.7 | 1 | 0.7 | 0 | 0 | 14 | 1.9 | 1 | 0.4 | 13 | 2.0 |
(0.9–2.8) | (0.0–4.0) | — | (1.0–3.1) | (0.0–2.0) | (1.1–3.5) | |||||||
C70–C73: brain | 8 | 3.8 | 3 | 8.5 | 6 | 6.4 | 5 | 3.2 | 8 | 6.7 | 3 | 2.3 |
(1.6–7.4) | (1.6–25.3) | (2.3–14.1) | (1.0–7.6) | (2.9–13.2) | (0.4–6.9) | |||||||
C81: Hodgkin's disease | 36 | 16.7 | 9 | 14.6 | 33 | 17.9 | 12 | 12.9 | 34 | 18.1 | 11 | 12.3 |
(11.7–23.1) | (6.6–27.9) | (12.3–25.2) | (6.7–22.7) | (12.5–25.3) | (6.1–22.1) | |||||||
C91–C95: leukaemias | 12 | 5.7 | 1 | 2.9 | 8 | 8.4 | 5 | 3.4 | 5 | 4.3 | 8 | 6.3 |
(2.9–10.1) | (0.0–16.7) | (3.6–16.7) | (1.1–7.9) | (1.3–10.0) | (2.7–12.6) | |||||||
All non-AIDS defining | 135 | 2.2 | 35 | 2.5 | 74 | 4.6 | 96 | 1.6 | 87 | 3.6 | 83 | 1.7 |
Cancers | (1.9–2.7) | (1.7–3.4) | (3.6–5.8) | (1.3–2.0) | (2.9–4.4) | (1.3–2.1) |
SIR=Standardized Incidence Ratios; CI=Confidence Intervals; KS=Kaposi's Sacroma; NHL=Non-Hodgkin Lymphoma; ICC=Invasive Cervical Cancer. IDU=Intravenous drug user.
310 cases among homosexual and bisexual men, SIR=6066, 95% CI: 5409–6780.
Three cases among homosexual and bisexual men, SIR=56.4, 95% CI: 10.6–167.0.