Table 8. Meta-analysis of the studies performed in neuroendocrine tumoral lung cancer, with their characteristics.
|
Group of neuroendocrine tumoral lung cancer (n=3) | |||||||
|---|---|---|---|---|---|---|---|
| Study | Method | Threshold | QS (%) | N Pts | Bcl-2+ (%) | HR | 95% CI |
| Brambilla et al (1996) | IHC-clone 124 | >50 | 41 | 43 | 56 | 11.48 | 1.34–98.01 |
| Eerola et al (1999) | IHC-clone 124 | NM | 45 | 20 | 18 | 0.44 | 0.13–1.43 |
| Santinelli et al (1999) | IHC-clone 124 | NM | 49 | 23 | 61 | 1.81 | 0.57–5.77 |
| Overall (fixed-effects model) | 86 | 55 | 1.26 | 0.58–2.72 | |||
| Overall (random-effects model) | 1.71 | 0.35–8.41 | |||||
| χ2 statistic for heterogeneity=6.79, 2 df, P=0.03 | |||||||
The meaning of the symbols is described in Table 3.