Table 1. Categorical distributions of baseline characteristics of patients and CA9/β-actin levels.
|
Total group of patientsa |
||||
|---|---|---|---|---|
| Variable | n | % of 253 | 10−4 CA9/β-actin median (interquartile range) | P |
| Age (years) | ||||
| <50 | 57 | 22.5 | 1.3 (8.8) | |
| ⩾50 | 196 | 77.5 | 1.6 (6.8) | 0.656c |
| Nodal statusb | ||||
| Negative | 103 | 40.7 | 1.0 (7.2) | |
| 1–3 nodes | 78 | 30.8 | 1.6 (6.2) | |
| ⩾4 nodes | 44 | 17.4 | 1.3 (7.9) | 0.624d |
| Menopausal status | ||||
| Premenopausal | 64 | 25.3 | 1.3 (8.7) | |
| Postmenopausal | 189 | 74.7 | 1.6 (6.7) | 0.878c |
| Tumour size | ||||
| pT1 | 66 | 26.1 | 1.2 (7.0) | |
| pT2 | 137 | 54.2 | 1.5 (5.8) | |
| pT3+pT4 | 46 | 18.2 | 3.0 (1.6) | 0.611d |
| Histological grade | ||||
| I/II | 84 | 33.2 | 1.1 (2.7) | |
| III | 86 | 34.0 | 4.2 (18) | |
| Unknown | 83 | 32.8 | 1.8 (6.6) | 0.009d |
| ER (fmol mg−1 protein) | ||||
| <10 | 88 | 34.8 | 7.2 (27) | |
| ⩾10 | 161 | 63.6 | 0.82 (2.7) | <0.001c |
| PgR (fmol mg−1 protein) | ||||
| <10 | 103 | 40.7 | 6.2 (23) | |
| ⩾10 | 147 | 58.1 | 0.84 (3.1) | <0.001c |
| Surgery | ||||
| Mastectomy | 183 | 72.3 | 1.5 (6.9) | |
| Breast-saving procedure | 70 | 27.7 | 1.2 (7.1) | 0.902c |
| Adjuvant radiotherapy | ||||
| None | 68 | 26.9 | 1.3 (6.6) | |
| Any | 184 | 72.7 | 1.5 (7.4) | 0.822c |
| Adjuvant systemic therapy | ||||
| None | 126 | 49.8 | 1.7 (8.2) | |
| Endocrine | 85 | 33.6 | 1.5 (5.3) | |
| Chemo | 28 | 11.1 | 1.0 (5.6) | |
| Both | 14 | 5.5 | 2.8 (15) | 0.735d |
a
Owing to missing values data do not always add up to 253.
b
All patients with uncertain number of involved lymph nodes are node positive.
c
P for Mann–Whitney U test.
d
P for Kruskal–Wallis test.