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. 2003 Jul 15;89(2):391–397. doi: 10.1038/sj.bjc.6601037

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Copyright © 2003 Cancer Research UK

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Levels of phospho-AKT (serine-473) and actin in the two human pancreatic cancer cell lines MIA-PaCa-2 and PANC-1, with the human prostate cancer cell line LNCaP as a positive control, which harbours a mutation in PTEN and thus demonstrates constitutive activation of PI3K (Davies et al, 1999).